Its concentration in serum rises only in cases of increased remodeling of bone.8 The tissue mineralization stimulating effect of BALP is achieved mainly through inactivation of pyrophosphate and osteopontin
, which are themselves mineralization inhibitors.9 Calcium and phosphate are important components of bony inorganic matrix and major factors in maintenance of bone health.
In other studies, osteopontin
, a biomineralization factor and a cellular matrix protein that plays an important role in the inflammation process, has been mentioned (19).
Studies have shown that salivary acid phosphatase, alkaline phosphatase, osteopontin
and osteocalcin levels had significantly improved following topical administration of melatonin.
Prespecified statistical analyses of PFS according to expression of two plasma biomarkers, TGF receptor III and osteopontin
, also did not achieve statistical significance.
The HART AKI test algorithmically interprets six clinical and protein variables (history of diabetes, blood urea nitrogen to creatinine ratio, C-reactive protein, osteopontin
, CD5 antigen-like, and Factor VII).
While many factors contribute to blood cell differentiation, secretion of a protein called osteopontin
was most highly correlated with better survival rates in mice treated with MSCs.
To determine that differentiation had happened, the specific gene of osteogenic cells, osteopontin
and collagen type I, was tested in both groups via RT-PCR.
27 Masloub SM, Abdel-Azim AM, Elhamid ESA: CD10 and osteopontin
expression in dentigerous cyst and ameloblastoma, Diagnostic pathology 2011, 6:1
Some studies have reported that resveratrol can up-regulate translation of Bone Morphogenic Protein-2 (BMP-2), Bone Morphogenic Protein-7 (BMP-7) and OPN (Osteopontin
In a previous study, researchers demonstrated that virus-mediated expression of osteopontin
and insulin-like growth factor (IGF1) promoted the regrowth of brain-derived corticospinal tract (CST) axons and functional recovery of CST-dependent motor function following an incomplete SCI lesion.
However, recent studies have shown that CAC is an organized, regulated, proactive process. CAC involves expression of an altered phenotype of vascular smooth muscle cells (VSMCs) and expression of bone-related proteins such as osteopontin
, osteoprotegerin (OPG), osteocalcin, and bone morphogenetic proteins (BMPs).