A new study in Biological Psychiatry has linked signs of heightened arousal and reactivity a core symptom of posttraumatic stress disorder (PTSD) to overactivity
of the locus coeruleus (LC), a brain region that mediates arousal and reactivity.
Results: Among 140 study participants detrusor overactivity
was found in 100 patients out of which 76 (76%) had thoracic level of injury, 20 (20%) had cervical level and 4 (4%) had lumbar level of injury.
The resulting motor neuron overactivity
causes excessive secretion of acetylcholine.
This autoimmune disease is caused by overactivity
of the entire thyroid gland.
The presence of detrusor overactivity
(DO) may have some implication on surgery outcome and additional management; however, about 30% of the patients with mixed stress and urgency incontinence will see improvement in both components after surgery.
Increased urgency, or painful sensations during filling CMG, can be an indication of inflammation, infection, detrusor overactivity
, neuralgia, and more.
Symptoms of ADHD include impulsivity, overactivity
, and inattention.
8] Moreover, sympathetic overactivity
and decreased responsiveness by the [beta] adrenergic metabolic receptors have been stated as the underlying mechanism for the linkage between weight gain and hypertension.
Dr North said: "It can be difficult to tell an allergic rash or swelling from one that occurs due to overactivity
of the immune system as with spontaneous urticaria.
Family and twin studies confirm that chronic insomnia can have a genetic component (heritability coefficients between 42% and 57%), whereas the investigation of autonomous and central nervous system parameters has identified hyperarousal as a final common pathway of the pathophysiology, implicating an imbalance of sleep-wake regulation consisting of either overactivity
of the arousal systems, hypoactivity of the sleep-inducing systems, or both.
The aim of this study was to prove the in vivo efficacy of Gegen on improving detrusor overactivity
and its possible synergism with darifenacin (a first-line muscarinic receptor-3 inhibitor) in spontaneously hypertensive rats (SHR), a rat model exhibiting symptoms of detrusor overactivity
Results: Urgency was the predominant urinary symptom, and detrusor overactivity
was the major bladder dysfunction.