Primary hyperparathyroidism is accompanied by oversecretion
of parathormone, leading to hypercalcemia and hypophosphatemia.
When IL-33 binds to its receptor, it can activate the MyD88 and NF-?B pathways, thereby promoting the Th2 cytokine response. Previous study showed that the plasma level of IL-33 is elevated in patients with asthma. In accordance with this, we also showed that nasal administration with IL-33 can replicate the typical characteristics of the airway Th2 immune response and abnormal airway remodeling. Furthermore, IL-33 monoclonal antibody can significantly attenuate allergen-induced eosinophil infiltration, mucus oversecretion
, and Th2 cytokine response in asthma mouse model.
In addition, the deposition of immune complexes on the bone marrow and oversecretion
of cytokines by uncontrolled T-cell activation stimulate the uncontrolled phagocytosis [8, 9, 19].
The very rare cause of GH oversecretion
is ectopic tumour .
Stimuli including overnutrition, physical inactivity, and ageing might lead to oversecretion
of proinflammatory cytokine, ultimately resulting in insulin resistance, diabetes, and its cardiovascular complications.
of interleukin-15 from skeletal muscle reduces adiposity," American Journal of Physiology-Endocrinology and Metabolism, vol.
Insulin resistant individuals maintain euglycaemic status at the expense of pancreatic oversecretion
as indicated by the high insulin values.
The etiology of prediabetes is primarily skeletal muscle, liver, and/or adipose tissue insulin resistance that, in time, promotes oversecretion
of insulin from the [beta]-cell and results in pancreatic exhaustion that leads to severe hyperglycemia .
HHM is associated with 80 percent of MAHs and is caused by the effects of the oversecretion
of parathyroid hormone-related peptide (PTHrP) [1-3].
represented by the goblet cell hyperplasia was also observed in the OVA-induced injury group (Figure 4(a)(B)).
Additionally, acupuncture at PC6 inhibited the oversecretion
of plasma CORT and reduced the increased levels of amygdaloid NE and MHPG following ARS.
Another study showed that the permeability of the parotid basal cell membrane was increased in diabetic patients, resulting in substantial glucose oversecretion
from theparotid duct .