When the gonads are asymmetrical the most likely cause is ovotesticular DSD (true hermaphrodite), butin about 20% of the cases karyotype may be 46XX/46XY.18 Ovotestes
with bipolar distribution of testicular and ovarian tissue is the most common type of gonad found in these children.24 Rarely both the gonads may be testes (XX testicular DSD) (Figure-4).
While it is most common for individuals to develop as hermaphrodites with ovotestes
(gonads largely composed of ovarian tissue with small pockets of testicular tissue; Cole and Noakes, 1997; Sakakura et al., 2006), they also can develop directly as males (primary males; Harrington, 1967; Ellison et al., 2015) or can undergo sex change from functional hermaphrodites to secondary males (Harrington, 1971; Turner et al., 2006).
The gonads may be any combination of ovary, testes or combined ovary and testes called ovotestes
. Although the external genitalia are usually ambiguous, they may vary from normal male to normal female.
However, later an examination of the deceased shark revealed that it possessed fully formed male and female reproductive tracts, including ovotestes
, an organ possessing both testicular and ovarian features.
When the shark was examined internally, however, it was found to have a complete pair of ovotestes
-gonads that contain both ovarian and testicular tissue.
exist in true hermaphrodites with a spectrum of functional qualities.
A hermaphrodite dog with bilateral ovotestes
Case report: ultrasonographic appearance of ovotestes
in a true hermaphrodite.
The testes or testicular components of the ovotestes
in ovotesticular DSD are likely to be dysgenetic, and gonadal tumors with a potential for malignancy occur in 2.6% of all cases (7).
Basophilic adenoma and ovotesticular fibrillar inclusions were also observed in the ovotestes
of snails exposed to the test metals .
(6-8) In addition, 3 cases were excluded from a report due to the presence of ovary, ovotestes
or atypical Karyotype.
To explain virgin birth, Professor Sam Berry states that Mary must have suffered from some chromosome abnormalities or must have had ovotestes
', which, for the uninitiated, are what a woman would have if she inherited from her father an X chromosome carrying SRY material, which is usually found on the Y chromosome.