10,335,391 covering methods of treating facial erythema associated with rosacea using a 1.0% w/w oxymetazoline
Only recently have we had Food and Drug Administration-approved treatments for the persistent facial erythema of rosacea, the alpha-adrenergic agonists brimonidine and oxymetazoline
. Other potential off-label treatments for facial erythema of rosacea include vascular lasers, oral beta-blockers or alpha-agonists, and even botulinum toxin.
These include oxymetazoline
, pseudoephedrine and phenylephrine.
Using a decongestant nasal spray such as oxymetazoline
(Afrin) for too long could make congestion levels worse, so people should not use them for longer than the recommended duration outlined on the packaging.
At our hospital, ESS begins with packing of the involved side of the nose and middle meatus with oxymetazoline
packs for a few minutes.
x 2 in., Medtronic Xomed, Inc., Jacksonville, FL) comprising a 1:1 solution of 4% lidocaine hydrochloride (Roxane Laboratories Inc., Columbus, OH) and 0.05% Oxymetazoline
Hydrochloride (Major[R] Soothing 12 Hour Nasal Decongestant Spray, Major Pharmaceuticals, Livonia, MI).
Latin Square) crossover pharmacokinetic study determined the impact of nasal inflammation on the absorption and bioavailability of testosterone from TNG and assessed drug-drug interactions of TNG when symptomatic patients were also treated with a common nasal decongestant, oxymetazoline
. An allergy challenge chamber (ACC) was used.
Use of oxymetazoline
in the management of epistaxis.
(24) studied alpha-2 adrenoceptor agonists, including dexmedetomidine, clonidine and oxymetazoline
, combined with lidocaine in male guinea pigs.
THURSDAY, May 17, 2018 (HealthDay News) -- Oxymetazoline
is safe and effective for the treatment of moderate-to-severe persistent erythema of rosacea, according to a study published in the June issue of the Journal of the American Academy of Dermatology.
For persistent erythema, topical alpha-adrenergic receptor agonists including brimonidine tartrate and oxymetazoline
have been shown to reduce erythema by vasoconstricting blood vessels, although some products are associated with a rebound erythema on treatment discontinuation.
Short-acting drugs such as chlorpheniramine maleate 25 mg and oxymetazoline
nasal drops 0.05% were administered sos to control severe symptoms in sneezers and nasal blockers, respectively.