Out of the total 300 patients, 136 patients required only packed red cells
When she examined details of each patient's transfusion protocol, it was immediately apparent that the protocol of a one-to-one or higher ratio of fresh frozen plasma to packed red cells
was not being applied.
Significant differences between the survivors and non-survivors in this series were found with respect to systolic blood pressure (SBP), the number of packed red cells
required in the first 24 hours, serum lactate concentration, pH on the initial arterial blood gas analysis, the first recorded temperature and haemoglobin concentration.
The hemoglobin concentration is calculated by determining the density of the centrifugally packed red cells
by measuring the depth of the float in the packed red cells
and correcting its depth and by accounting for the floatation forces of the huffy coat.
Treatment requires antigen-reduced packed red cells
to control symptoms, and iron overload should be diminished by concurrent use of chelation therapy.
Reporting the frequency of their crises, hospitalization and packed red cells
transfusion every month for six months.
Fluid resuscitation with packed red cells
should be initiated immediately, combined with the correction of clotting defects if present.
These different causes probably account for the finding that despite similar baseline haemoglobin values between the groups, HIV-positive patients received more transfusions of packed red cells
than HIV-negative patients.
Table 2 compares the means of test results and other variables in individuals who had red cell cobalamin concentrations above and below the cutoff of 33 pmol/L packed red cells
She was also aggressively resuscitated with intravenous fluids, receiving four units of packed red cells
, two units of fresh frozen plasma and two litres of crystalloid.
The patient was transfused two units of packed red cells
, after which his hemoglobin increased to 8.
Some factors can affect spun microhematocrit readings, including improper sealing of the capillary tube resulting in blood loss from the tube, not mixing the specimen, the time and speed of centrifugation outside the standard five minutes at 10,000 to 15,000 RPM, incorrect reading with the hematocrit reader, excessive trapped plasma in the packed red cells
such as from neonate hyperviscosity syndrome, dehydration of the patient, capillary tube size outside the usual 75mm with 1.