pancreatic islets


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Related to pancreatic islets: pancreas, islets of Langerhans, insulin

pancreatic islets

(or islets of Langerhans) Scattered endocrine regions in the pancreas that produce glucagon and insulin.
References in periodicals archive ?
Pancreatic islets will be microencapsulated in E--Gels; biofunctionalised injectable hydrogels containing immunosuppressive agents and polymeric microparticles with tuneable degradation profiles for localised delivery of efficacy cues.
T1DM disease is caused by the triggering of an autoimmune response against the beta cells of the pancreatic islets, which are destroyed over the course of several months, resulting in insulin dependency.
KYOTO - Kyoto University Hospital said Friday it successfully transplanted pancreatic islets from a brain-dead donor to a diabetes patient on Sunday.
It contains 11 chapters by surgeons from the US and UK who discuss living donation, new surgical techniques, living-donor liver transplantation, antibody-incompatible transplantation, pancreas transplantation, allotransplantation of pancreatic islets, new cell therapies, intestinal transplantation, pediatric renal transplantation, and immunosuppressive pharmacotherapy.
Their pancreatic islets secreted high levels of insulin in the presence of increasing glucose concentrations and 30 mM K(+).
The research team engineered a biomaterial to protect the cluster of insulin-producing cells - donor pancreatic islets - during injection.
The team now intends to develop methods for the mass generation of pancreatic islets at lower cost for the treatment of diabetes through transplantation, while working towards shortening the one-month period currently required for creating pancreatic islets.
As Boswellia serrata (boswellia) has been shown in a number of studies to possess anti-inflammatory activity, the researchers here set out to see if it could modulate the development of type 1 diabetes and prevent hyperglycemia, inflammation of pancreatic islets and increase of proinflammatory cytokines in a murine model.
Previously, Unniappan's team studied mice and found similar results; not only was insulin secretion stimulated, but nesfatin-1 was observed to be lowered in the pancreatic islets of mice with Type 1 diabetes and increased in those with Type 2 diabetes.
As time passes, the pancreatic islets in the liver will take up new blood supply, and the patient's requirement of exogenous insulin is expected to decrease, facilitating diabetes management and preventing the onset of complications of the disease, and ultimately improving his quality of life.
We are now working on an experimental gene therapy by delivering adenovirus-mediated TRAIL gene into pancreatic islets.
RAMAN SPECTROSCOPIC ANALYSIS OF PANCREATIC ISLETS Kimberly Hobbs, Emanuel Waddell, Adriel D.