SERAXIS' leading technology includes GMP-grade, pure pancreatic islets
that contain 60-90% of insulin-secreting beta cells.
Insulin dependent diabetes is a multifactorial disorder that could be theoretically cured by functional pancreatic islets
and autologous insulin producing cells, or AIP cells, implantation.
The alcoholism has a major effect on pancreatic islets
cells and their insulin secretion.
[USA] Aug 31(ANI): Insulin, a peptide hormone produced by beta cells of the pancreatic islets
, boosts immune health, according to a new study.
The Seraxis investigators further showed that the islet clusters functioned like mature pancreatic islets
, secreting insulin shortly after transplantation in response to fluctuations in glucose in a rodent model of diabetes.
Summary: TEHRAN (FNA)- Researchers tissue-engineered human pancreatic islets
in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice.
The functional impairment and death of pancreatic islets
by IBMIR is usually ascribed to multiple pathological effects.
Intrahepatic transplantation of pancreatic islets
(PIs) represents an alternative treatment for unstable type 1 diabetic patients , but the procedure is associated with partial damage of liver tissue [2,3] and graft impairment due to blood-mediated inflammation, rejection, or hypoxia .
Replacement strategies include the transplantation of whole human/porcine pancreatic islets
, beta cell pseudoislets, or the application of islet progenitors derived from induced pluripotent stem cells (iPSCs) [4, 5].
Uskokovic et al., "Protective effects of the mushroom Lactarius deterrimus extract on systemic oxidative stress and pancreatic islets
in streptozotocininduced diabetic rats," Journal of Diabetes Research, vol.