Combined with the test results of the increased biliary system pressure, bile and pancreatic juice
discharging, ALO-induced pancreatitis was considered as the pathogenesis in this case.
A mild elevation of serum amylase levels can be seen in patients with post-ERCP perforation as a result of absorption of pancreatic juice
in the retroperitoneal space.
Food passes through the esophagus to the jejunal loop, and mixes with bile and pancreatic juice
40 cm below.
Yu and colleagues (47) analyzed the pancreatic juice
of patients with PDAC (34 cases), patients with IPMN (57 cases), and controls with normal pancreas or chronic pancreatitis (total of 24 cases).
In contrast to the unaffected basal pancreatic secretory function, we have observed that amylase secretion induced by caerulein or by diversion of pancreatic juice
to the exterior (DPJ) was markedly reduced in the adult rats pretreated in the suckling period of life with LPS, as compared to the untreated control.
For this reason, the miRNA has been isolated and studied from pancreatic tumor tissue, blood samples (serum, plasma), pancreatic juice
, stool, urine, and even saliva.
There were 80 studies that detected miRNAs in the blood (such as whole blood [14, 46, 53, 54], serum [24, 27, 28, 30, 32, 39, 40, 50, 51], and plasma samples [3, 11-13, 21, 23, 26, 33, 34, 36-38, 52]), and 29 studies detected miRNA in nonblood samples (including tissues [41-43, 45, 47-49, 55], pancreatic juice
, and stool [22, 25, 31, 35]).
Unfortunately, we also found trace amounts of pancreatic juice
in the drainage fluid from the peripancreatic space.
It was found that pancreatic juice
was leaking from the edge of the omental patch.
Elastase is an acidic protease present in the pancreatic juice
(9) In patients with pancreatic trauma who have survived the initial 48-72 hours, leakage of corrosive pancreatic juice
from an undiagnosed injured duct causes peripancreatic inflammation and may result in sepsis, which is the major cause of morbidity and mortality.