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 (pə-păv′ə-rēn′, -ər-ĭn)
A nonnarcotic alkaloid obtained from the opium poppy, C20H21NO4, structurally distinct from morphine and other opiates, used in its hydrochloride form to relieve spasms of smooth muscle.

[Latin papāver, poppy + -ine.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(pəˈpeɪvəˌriːn; -rɪn)
(Elements & Compounds) a white crystalline almost insoluble alkaloid found in opium and used as an antispasmodic to treat coronary spasms and certain types of colic. Formula: C20H21NO4
[C19: from Latin papāver poppy]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(pəˈpæv əˌrin, -ər ɪn, pəˈpeɪ vəˌrin, -vər ɪn)

a white, crystalline alkaloid, C20H21NO4, used as a smooth-muscle relaxant.
[1855–60; < Latin papāver poppy + -ine2]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.papaverine - an alkaloid medicine (trade name Kavrin) obtained from opium; used to relax smooth muscles; it is nonaddictive
muscle relaxant - a drug that reduces muscle contractility by blocking the transmission of nerve impulses or by decreasing the excitability of the motor end plate or by other actions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
We present a case of a paraplegic and parastetic patient who developed a penile abscess due to intracavernosal papaverine injections.
Buffered papaverine facilitates passage of intratympanic dexamethasone to the inner ear.
Following explantation, the RA was first stored in a solution of blood, heparin, and papaverine. We then used the 'skeletonized technique' to free the artery from excess tissue using metallic clips.
Effects of papaverine in hepatic ischemia-reperfusion injury in rats.
In addition, intracavernosal injections with phentolamine, papaverine and alprostadil have been used successfully (80%) for improvement of erectile dysfunction by releasing higher levels of cyclic adenosine monophosphate, another potent dilatator, despite undesirable side effects such as priapism and hematoma (16).
An observational cross-sectional study was conducted : Department of IGIMS, Patna from 6/4/17 to 30/12/ total of 21 consecutive patients presenting with erectile dysfunction were included and all underwent penile c Doppler evaluation with injection of papaverine 2 mL intracavernosal used in this study.
Poppi, "Simultaneous determination of dipyrone and papaverine in pharmaceutical formulation using PLS regression and UV spectrophotometry," Analytical Letters, vol.
For the latter, continuous intra-arterial infusion of vasodilators, such as papaverine hydrochloride, is useful.
Effect of Papaverine Applications on Blood Flow of the Internal Mammary Artery.
The study enrolled 71 otherwise healthy subjects with idiopathic IBS that knowingly decided to follow one of these management strategies: Hyoscine butylbromide, administered when needed (Group 1); papaverine hydrochloride 10 mg + belladonna extract 10 mg, administered when needed (Group 2); supplementation with Casperome, 1 tablet of 250 mg per day, for four weeks (Group 3).
CryoLife vascular allografts are processed with papaverine hydrochloride and antimicrobials, packaged and then supercooled and stored in liquid nitrogen following patented processes and in accordance with the American Association of Tissue Banks (AATB) guidelines (CryoLife, Inc., 2016a).
Arterial vasodilators (reserpine, papaverine, tolazoline), specific thromboxane inhibitors (methimazole, iloprost), and nonspecific thromboxane inhibitors (aspirin, methylprednisolone) are also recommended to prevent edema, thrombosis, and vasospasm (6).