parabiosis


Also found in: Medical, Encyclopedia, Wikipedia.

par·a·bi·o·sis

 (păr′ə-bī-ō′sĭs)
n. pl. par·a·bi·o·ses (-sēz)
1. The natural or surgical union of anatomical parts of two organisms, usually involving exchange of blood, as in the development of conjoined twins or in certain transplant operations.
2. A temporary suspension of conductivity or excitability in a nerve.

par′a·bi·ot′ic (-ŏt′ĭk) adj.
par′a·bi·ot′i·cal·ly adv.

parabiosis

(ˌpærəbaɪˈəʊsɪs)
n
1. (Biology) the natural union of two individuals, such as Siamese twins, so that they share a common circulation of the blood
2. (Biology) a similar union induced for experimental or therapeutic purposes
[C20: from para-1 + Greek biōsis manner of life, from bios life]
parabiotic adj

par•a•bi•o•sis

(ˌpær ə baɪˈoʊ sɪs, -bi-)

n.
the physiological or anatomical union of two individuals.
[1905–10]
par`a•bi•ot′ic (-ˈɒt ɪk) adj.

parabiosis

the uniting of two individual organisms or animals anatomically and physiologically, either under experimental or natural conditions. — parabiotic, adj.
See also: Joining
the uniting of two individual organisms or animals anatomically and physiologically, under either experimental or natural conditions. — parabiotic, adj.
See also: Biology
Mentioned in ?
References in periodicals archive ?
This was demonstrated in a series of parabiosis studies whereby the circulatory systems of old mice were joined together with young mice.
Consequently, Karmazin said he was inspired by the concept of parabiosis, which connects the veins of two living animals.
Heterochronic parabiosis experiments, in which a young and old mice are surgically linked so they develop a shared blood circulation [60], indicate that signals from a young circulation can impact the function of aging tissues [61].
It is based on research into the effects of parabiosis, tested in experimental mouse studies.
Under steady-state conditions, the replenishment of AMs in humans and mice occurs mainly via self-renewal as recently demonstrated in long-term lung transplant, parabiosis, and fate-mapping studies [43-45].
Seminal parabiosis experiments in inbred strains of mice with severe obesity (ob/ob and db/db rodents) led to the notion that a circulating factor, leptin, regulated body weight (5-7).
The process pioneered by the scientists is called parabiosis, and it consists of connecting young and old mice with the same blood system.
The proposed treatment has a root in modern science that traces back to 1864, when a scientist first described parabiosis, which is when two organisms are surgically connected such that blood circulates between the both of them.
An elegant study performed by Loffredo and colleagues [200] demonstrated that changing the systemic influence from the blood by connecting young to aged blood by parabiosis (surgical technique that unites the vasculature of two living animals) showed that after 4 weeks, aged rats that were exposed to young circulation had reversed age-related cardiac hypertrophy, resulting in cardiovascular protection.
This artificial joining of two separate animals, known as parabiosis, was a staple of physiology experiments for over a century before Irina Conboy got the idea to pair an old mouse with a young one.
After this procedure, called parabiosis, blood vessels grew and joined the rats' circulatory systems.