paracrine


Also found in: Medical, Encyclopedia, Wikipedia.
Related to paracrine: Paracrine signaling

par·a·crine

 (păr′ə-krĭn′, -krēn′)
adj.
Of or relating to the release of locally acting substances from endocrine cells.

[German parakrin : Greek para-, para- + Greek krīnein, to separate; see krei- in Indo-European roots.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

paracrine

(ˈpærəˌkriːn)
adj
(Physiology) relating to a hormone whose release only affects tissue surrounding the gland that secreted it
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
The research team concluded that "feto-maternal and maternalafetal trafficking of exosomes indicative of paracrine signaling during pregnancy.
The hMSCs were used because of their prominent paracrine activity of secreting good proteins to promote the regeneration of blood vessels and the endothelial cell survival.
Stem cells and stem cell therapy work by paracrine signaling to create the appropriate healing environment to restore tissue.
Many researchers believe that the beneficial effects provided by BMSCs transplantation would be primarily based on their paracrine activity by releasing trophic and immunomodulatory factors (27).
Epicardial adipose tissue (EAT), avisceral adipose tissue surrounding the heart and the coronary arteries, has endocrine and paracrine activity.
[USPRwire, Fri Sep 28 2018] According to a new market research report "Cell Signaling Market by Type (Endocrine, Paracrine), Pathway (Akt, AMPK, Hedgehog, Notch), Product (Consumables, Instruments), Technology (Flow Cytometry, ELISA, Mass Spectrometry) & Application (Research, Cancer, Immunology) - Global Forecast to 2022", published by MarketsandMarketsao.
[ClickPress, Fri Sep 28 2018] According to a new market research report "Cell Signaling Market by Type (Endocrine, Paracrine), Pathway (Akt, AMPK, Hedgehog, Notch), Product (Consumables, Instruments), Technology (Flow Cytometry, ELISA, Mass Spectrometry) & Application (Research, Cancer, Immunology) - Global Forecast to 2022", published by MarketsandMarketsao.
These results suggest a novel pathophysiological hypothesis in which chronic constipation may reflect a paracrine hormone insufficiency of pro-uroguanylin in the small intestine.
It actually serves as an endocrine and paracrine organ, contributing to the homeostasis of body energy, lipid and carbohydrate metabolism, having vasocrine regulative functions in the heart, being a major source of anti-inflammatory and proinflammatory adipokines, and considered a potential risk factor for cardiovascular diseases such as coronary syndromes (13).
well-organized, auto- and paracrine mediated physicochemical barrier