The bag contained anti-seizure drug Paraldehyde
in a 50ml brown bottle with a white safety cap, and a 7.5ml syringe of Midazomal.
After she can speak again, she has the temerity to complain about headaches, so the nurses stick a tongue depressor into her mouth and pour paraldehyde
down her throat, which (paradoxically) causes an epileptic seizure.
The use of sedatives, chloral hydrate and paraldehyde
, were preferable to opiates that should be avoided.
Of those, isoniazid and paraldehyde
act via specific mechanisms such as interference at the level of CNS receptors and ion channel function, depletion of GABA (isoniazid), impairment of the propagation of electrical activity in the CNS (paraldehyde
), and inflammation of the GI mucosa (paraldehyde
) (Gilman, 1985; Carpentier et al., 1992).
It proposed some drugs that cause halitosis; lithium salts, penicillamine, griseofulvin, thiocarbamide, dimethylsulfoxide, ethyl alcohol, antihistaminics, diuretics, phenothiazines derivatives, tranquilizers, choral hydrate, nitrites and nitrates, amphetamines, paraldehyde
, suplatatosilate, bisphosphonates, metronidazole, arsenic salts (9).
In the latter study, the large neurons were the ones staining stronger both with paraldehyde
fuchsin and against serotonin, which is in accordance with the present observation in neurons of Scrobicularia plana.
The inmate of Kirkdale Homes was believed to have drunk toxic paraldehyde
while at Walton Hospital.
* Waugh switched medication from chloral and bromide to paraldehyde
after his Pinfold episode; he risked depression by combining it with alcohol.