The tandem duplicated paralog
aqp1ab was also found in intestinal tissues and showed similar regulation to aqp1aa, although the effect of salinity was less pronounced.
Nevertheless, this paralog
is restricted to the apical membrane of flat and elongated epithelial cells (Chauvigne et al., 2013), and thus is similar to the localization of AQP 10 in rat efferent ducts (Hermo et al., 2004).
ZP domain proteins in the abalone egg coat include a paralog
of VERL under positive selection that binds lysin and 18-kDa sperm proteins.
EF484875-EF484878), signatures matching these sites could not be assigned to either paralog
. The 140 unique signatures comprise 45 perfect 17-bp matches to one or both of the C.
The most informative transcription factors are those that are used repeatedly in the course of vertebrate hematopoietic and immune processes, especially when this applies across vertebrate paralog
groups in vertebrates may in sum be larger than in amphioxus and S.
ABR is a regulator of the RHO family of small GTPases, signaling proteins involved in cytosketal dynamics, and a paralog
of the BCR (BCR activator of RhoGEF and GTPase) gene.
(2017), using the full genome Illumina HiSeq sequencing, observed three putative genes, fliCl, fliC2, and fliC3, encoding three different paralog
The company added that BLU-554 (CS3008) is an oral, potent highly selective and irreversible inhibitor of FGFR4, with a precise selectivity for FGFR4 that spares the paralog
kinases FGFR1, FGFR2 and FGFR3.
CHD5, a brain-specific paralog
of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes.
Aplysianin-A is a paralog
of escapin, found in the albumen gland and egg masses of Aplysia californica (Cummins et al., 2004); and orthologs of aplysianin-A are present in Aplysia kurodai (Jimbo et al., 2003).
On the other hand, the domain DUF1088 (domain of unknown function 1088) is shared only by LRBA and its paralog
neurobeachin, which may indicate specific functions of these two proteins not shared by other members of the BDCP.