paroxetine


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par·ox·e·tine

 (pă-rŏk′sĭ-tēn′)
n.
A drug of the SSRI class, C19H20FNO3, used in its hydrochloride form to treat depression, anxiety, and certain other disorders, including obsessive-compulsive disorder.

[par(a)- + ox(y)- + (m)et(hyl) + (piperid)ine.]

paroxetine

(pæˈrɒksətiːn)
n
(Pharmacology) an antidepressant drug that acts by preventing the re-uptake after release of serotonin in the brain, thereby prolonging its action: used for treating depression, obsessive-compulsive disorders, and panic disorder. Formula: C19H20FNO3
Translations

paroxetine

n paroxetina
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References in periodicals archive ?
Lupin Pharmaceuticals Inc, the US arm of Indian pharmaceutical firm Lupin (NSE: LUPIN), is recalling 12,480 bottles of Paroxetine extended-release tablets from the US market due to failed dissolution specifications, India's Economic Times reported on Wednesday.
Paroxetine is functionally classified as a Selective Serotonin Reuptake Inhibitor (SSRI) (9-12), which is used in the treatment of depression (13), generalized anxiety disorder (14), obsessive-compulsive disorder (15), panic (16) and post-traumatic stress disorder (17).
Objectives: To find out the possible effects of paroxetine on gastrointestinal smooth muscles in vitro as they can cause severe nausea and vomiting at the start of therapy which later settles down.
The London-based drug maker colluded with other companies from 2001 to 2004 by agreeing to make payments "and other value transfers totaling over 50 million pounds to suppliers of generic versions of paroxetine," the Competition and Markets Authority (CMA) said in a recent statement.
The CMAs decision relates to conduct and agreements between 2001 and 2004 in which GlaxoSmithKline plc (GSK), the supplier of branded paroxetine (an anti-depressant medicine), agreed to make payments and other value transfers totalling over 50 million to suppliers of generic versions of paroxetine.
5% carbomethoxycellulose), an oral dose of the vehicle alone (inactive control), or paroxetine hydrochloride (Paxil) dissolved in distilled water (active control).
Paroxetine is not a safe or effective drug for adolescent major depressive disorder, according to a re analysis of data from a prominent and controversial trial.
The periconceptional use of some selective serotonin reuptake inhibitors (SSRIs) appears to have no impact on the development of birth defects, but some birth defects occur more frequently among infants of women treated with paroxetine or fluoxetine early in pregnancy, results from a Bayesian analysis demonstrated.
8] Clinically it has been shown to be effective in both the short-term and long-term treatment of adults with major depressive disorder (MDD), [9] comparable in efficacy to selective 5-HT reuptake inhibitors such as fluoxetine, paroxetine, citalopram, and sertralin.
As a drug of the selective serotonin reuptake inhibitor (SSRI) type, paroxetine is mainly used for the treatment of depression, obsessive-compulsive disorder and social anxiety and is among one of the three SSRI drugs with certain efficacy (the other two being fluoxetine and paroxetine).
Based on the literature that examined the effectiveness of paroxetine in treating hot flashes, Noven, the manufacturer of BRISDELLE, hypothesized that a product with a paroxetine dose lower than those prescribed for psychiatric disorders could be effective in treating VMS.
With the approval of the antidepressant paroxetine (Brisdelle) by the Food and Drug Administration (FDA) to treat moderate to severe hot flashes, women may find the selective serotonin reuptake inhibitor (SSRI) drug as the non-hormonal answer to end their suffering.