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The development of a diseased or morbid condition.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌpæθəˈdʒɛnɪsɪs) or


(Pathology) the origin, development, and resultant effects of a disease
pathogenetic adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌpæθ əˈdʒɛn ə sɪs)

also pa•thog•e•ny

(pəˈθɒdʒ ə ni)

the production and development of disease.
path`o•ge•net′ic (-oʊ dʒəˈnɛt ɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pathogenesis - the origination and development of a disease
focalisation, focalization - the confinement of an infection to a limited area
pathologic process, pathological process - an organic process occurring as a consequence of disease
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n. patogénesis, origen y desarrollo de una enfermedad.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
The etiologic factors that cause sinonasal polyposis are still unclear, but there is evidence that cell-mediated immunity might play a role in its pathogenesis. [12-14] Leukotrienes have been shown to be elevated in some patients with sinonasal polyposis, especially those in whom polyposis defies conventional modalities of treatment.
In this edition of the textbook, Lowe and Anderson highlight histology that is relevant to disease processes, the structures and the structure-function relationships that are germane to disease pathogenesis, and histological structures that play key roles in disease pathogenesis in order to help students learn histology in the context of relevant clinical disease processes.
Another 17 papers by researchers in various biomedical sciences cover the virus evolution and pathogenesis of H5N1 infection in humans, the action of current anti-viral drugs and the design of novel ones, vaccines against influenza, resources for developing new influenza therapeutics, natural therapies, and prevention policies and their applications.
The organization of the subsequent chapters typically alternates between topics in cell biology and bacterial pathogenesis. For example, chapter 11 describes assembly of the cellular cytoskeleton, while chapter 12 describes the mechanisms used by pathogenic bacteria to manipulate the cytoskeleton.
The research team will also explore the possibility that certain autoimmune disorders may actually be collections of a number of so-called elemental disorders, each with its own pathogenesis and trigger.
Researchers survey targeted proteomics applications in biomedical areas, focusing in turn on biomarker discovery and pathogenesis, bioinformatics and other tools currently found useful in targeted proteomics, and biobanks of stored data.
Retroviruses; molecular biology, genomics and pathogenesis.
Tissue tropism and pathogenesis of influenza A virus subtype H5N1 disease in humans is not well defined.
The intent of this request for applications is to stimulate research that will increase fundamental knowledge of the cellular and molecular components and mechanisms and signaling processes that regulate the immune system in cardiovascular, pulmonary, and blood tissues, and that are important in healthy tissue maintenance, damaged tissue repair, and disease pathogenesis. Optional letters of intent are due 1 March 2001, with applications due 29 March 2001.
Among their topics are the comparative genomics and evolutionary analyses of human fungal pathogens, animal models of human fungal infection, virulence characteristics of Aspergillus fumigatus, pathogenesis mechanisms of Histoplasma capsulatum, Blastomyces dermatitidis and blastomycosis, and Paracoccidioides mechanisms of pathogenesis and virulence.
Coverage encompasses novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention.
Another is a statement that infection of endothelial cells is a critical event in the pathogenesis of Ebola virus, which, to my knowledge, has never been adequately documented.