There is limited information about pathogenetic
mechanisms explaining how ELC might correlate with atherosclerosis.
We have considered this mutation to be pathogenetic
because both MITOMAP and Yahram scoring support its pathogenicity.
The mechanism of amyloidosis of the urinary tract is still unknown; however, abnormal protein metabolism and chronic urinary tract infections or repeated inflammation of the mucosa or submucosa are the best pathogenetic
Activation of autoreactive B lymphocytes, leading to their differentiation into autoantibodies (auto-abs) producing plasma cells, is the most important pathogenetic
mechanism in several autoimmune diseases.
The mutation in intron 10 (c.1030-1G>A) of TSC1 might indicate a pathogenetic
mechanism which could be beneficial for differential diagnosis and future therapy exploring.
In contrast, the potential pathogenetic
role played by L.
The concurrence of ring constrictions in Adams-Oliver syndrome: additional evidence for vascular disruption as common pathogenetic
 This may be an additive pathogenetic
In vitro organ models allow complex organ development studies and pathogenetic
analyses to be carried out directly in human tissue.
mechanisms of PIS are still unknown: fever and leukocytosis have been attributed to an activation of the inflammatory pathways induced by the aneurysm exclusion and mediated by the release of several inflammatory cytokines including TNF-[alpha], IL-1 [alpha], IL-1[beta], and IL-6 [5-7].
demonstrated a novel pathway (Wnt/betacatenin/COX-2/VEGF) to play a pathogenetic
role in the development of retinopathies, and thus, this novel pathway might be a new target for future therapeutic approaches.
The use of preformed physical factors is reasonably considered a leading measure among the complex of pathogenetic
therapeutic measures against chronic inflammation of the uterine appendages.