It is associated with a pathological process
involving metabolism deregulation, protein misfolding, mitochondrial dysfunction, and neuroinflammation.
"Metastasis is a highly complex pathological process
. Increased specificity in defining the underlying principles is important to better understand and interpret the literature to move forward in the development of therapeutic interventions," explained Hurst.
These latter patients had symptoms suggesting intracranial complications resulting from a pathological process
in the middle ear.
If further studies show that the bacteria actually affects the pathological process
, it could lead to new therapeutic strategies using antibacterial agents.
Early identification of individuals at risk allows for early intervention to halt or reverse the pathological process
. Assessment of arterial stiffness by measurement of aortic pulse wave velocity (aPWV) is included in the latest guidelines for CVD risk prediction and is a key marker for hypertension.
According to the company the Cladribine tablets is an investigational agent that has been studied as a short-course (a maximum of 20 days of treatment over two years) oral therapy that is thought to selectively target lymphocytes, which may be integral to the pathological process
of relapsing MS.
This complicated pathological process
of excess fat and dysfunction is called adiposopathy, and it makes the treatment of obesity very difficult.
SAN DIEGO -- The apolipoprotein E e4 allele appears to help drive a key pathological process
in Alzheimer's disease: deposition of hyperphosphorylated tau protein.
It is not clear whether that decline is due to the pathological process
of schizophrenia or an existent low premorbid IQ.
In addition, the use of antibiotics would aggravate the above pathological process
. Dahuang could inhibit such bacteria translocation originating from burns, "two hits" from endotoxins, as well as the application of broad-spectrum antibiotics.[sup] In our subsequent experiments, we aimed to explore the feasibility and potential mechanism of Dahuang to improve the intestinal mucosal microcirculation in mice by observing changes in small intestinal mucosa, intestinal wall blood flow, and intestinal tissue oxygenation.
Internal root resorption is a pathological process
, initiated within the pulp space and associated with loss of dentine.
"This research suggests that magnetite from the environment may be another trigger in a cumulative pathological process
in which toxins combine with beta-amyloid--a hallmark protein of AD--to create increasingly higher levels of free radicals and inflammation that destroy more and more neurons," explains Greg Fricchione, MD, director of the Division of Psychiatry and Medicine at Massachusetts General Hospital (MGH) and MGH's Benson-Henry Institute for Mind Body Medicine.