The oral route is made largely ineffective due to the pathological state
of the patient (gastrointestinal tract motility, intubation, intestinal perforation, etc.).
To date, no effective antibiotic treatment is available for severe gastrointestinal infections because of the very nature of the disease: oral treatments struggle to reach the intestine because of the pathological state
of the patient (reduced gastrointestinal motility, intubation, intestinal perforation, etc.), while current intravenous antibiotics do not penetrate the gastrointestinal barrier and thus do not reach the infection site.
However, in adults, most of the cases are associated with a pathological state
and a lead point.
to an side There are bloggers who expend all their efforts in a pathological state
of intensity by pouring over everything to do with Rangers at the expense of writing about their own club.
The Food and Nutrition Research Institute (FNRI) of the Department of Science and Technology defines malnutrition as the pathological state
, general or specific, resulting from a relative or absolute deficiency or excess in the diet of one or more essential nutrients, which may be manifested clinically or detectable by physical, biochemical or functional signs or both.
Any imbalance precipitates a pathological state
known as "gut dysbiosis" .
Fatigue reflects a physiological, psychological, and potentially pathological state
that decreases an individual's energy.
Either directly through trauma, or indirectly through secondary disease indications, brain death is the final pathological state
that over 60 million people globally transfer through each year.
Hydrocephalus is a pathological state
of CSF accumulation, which leads to the dilatation of the cerebral ventricles.
Given that the predominant underlying pathological state
is one of severe axonal necrosis, rapid improvement is not expected.
Thus, the investigation of eye movements has been applied as an experimental tool over the past four decades and provides a unique opportunity to understand the functional integrity of brain structures both in the healthy brain and in pathological state
. The latter include the broad variety of Parkinsonian Syndromes  and other neurodegenerative conditions such as amyotrophic lateral sclerosis , fronto-temporal lobar degeneration , and Alzheimer's disease .