Immune Pharmaceuticals announced the acceptance of an abstract for a poster presentation at the 2018 Pre-IID Pemphigus and Pemphigoid
Symposium: "A New Era of Translation and Clinical Science," being held May 15-16, 2018 in Orlando, FL.
Bertilimumab is currently in phase 2 clinical trials for bullous pemphigoid
(BP) and ulcerative colitis (UC).
Burkhart, RDH, BS, NMEd, EdD, received the 2017 Dental Professional of the Year Award from the International Pemphigus & Pemphigoid
He gave one example of a patient who had been diagnosed with bullous pemphigoid
several years before, and who was becoming Cushingoid as a result of steroids.
4%) patients, followed by bullous pemphigoid
with 22 (25.
The company's lead product candidate, bertilimumab, is in Phase II clinical development for moderate-to-severe ulcerative colitis as well as for bullous pemphigoid
, an orphan autoimmune dermatological condition.
In this descriptive study 7 cases of bullous disorders was seen, out of which 4 cases (2%) had Bullous Pemphigoid
, 3 cases (1.
Other forms of pemphigus include the most serious one, pemphigus vulgaris (PV) and bullous pemphigoid
The company continues to accrue patients in two phase two clinical trials for bertilimumab, a first-in-class monoclonal antibody targeting eotaxin-1: an open label 10 patient trial in the treatment of bullous pemphigoid
, an orphan auto-immune dermatological condition, and a double-blind, placebo-controlled, 42 patient trial in moderate-to-severe ulcerative colitis, a gastrointestinal inflammatory condition.
However, a recent study of BSLE patients demonstrated that autoantibodies to other elements of the basement membrane including laminin-5, laminin-6, and bullous pemphigoid
(BP) antigen I are effective in the pathogenesis of BSLE.
is an autoimmune bullous disease characterized by skin lesions, with or without oral lesions.
Patients having unstable denture or with soft liners tissue conditioners and with uncontrolled medical problem like uncontrolled diabetes mellitus, uncontrolled bleeding disorders, pemphigus, pemphigoid
, lupus erythematosus were excluded.