pemphigus


Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

pem·phi·gus

 (pĕm′fĭ-gəs, pĕm-fī′gəs)
n.
Any of several acute or chronic skin diseases characterized by groups of itching blisters.

[New Latin pemphīgus, from Greek pemphīx, pemphīg-, pustule.]

pem′phi·gous adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

pemphigus

(ˈpɛmfɪɡəs; pɛmˈfaɪ-)
n
(Pathology) pathol any of a group of blistering skin diseases, esp a potentially fatal form (pemphigus vulgaris) characterized by large blisters on the skin, mucous membranes of the mouth, genitals, intestines, etc, which eventually rupture and form painful denuded areas from which critical amounts of bodily protein, fluid, and blood may be lost. Also (obsolete): pemphix
[C18: via New Latin from Greek pemphix bubble]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pem•phi•gus

(ˈpɛm fɪ gəs, pɛmˈfaɪ-)

n.
a skin disease characterized by blisters and ulcerations.
[1770–80; < New Latin < Greek pémphīx (s. pemphīg-) bubble]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pemphigus - a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membranepemphigus - a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane
autoimmune disease, autoimmune disorder - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
disease of the skin, skin disease, skin disorder - a disease affecting the skin
acantholysis - a breakdown of a cell layer in the epidermis (as in pemphigus)
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

pem·phi·gus

n. L. pénfigo, término usado para definir una variedad de dermatosis, cuya característica común consiste en la manifestación de ampollas que se infectan y revientan.
English-Spanish Medical Dictionary © Farlex 2012

pemphigus

n pénfigo
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
'During the second quarter we continued to execute on our clinical programs, including the global PEGASUS Phase 3 trial and a Phase 2 extension trial in patients with pemphigus, as well as our Phase 2 clinical trial in patients with immune thrombocytopenia,' said Martin Babler, president and chief executive officer of Principia Biopharma.
Summary: There is no particular cure for pemphigus vulgaris, but pemphigus vulgaris treatment can help prevent the aggravation of the symptoms.
The FDA approved Rituxan for rheumatoid arthritis (RA) in 2006, for the treatment of adults with GPA and MPA in 2011, and for adults with pemphigus vulgaris in 2018.
M2 PHARMA-June 17, 2019-Phase III PEMPHIX Study Showed That Genentech's Rituxan is Superior to Standard of Care in Achieving Sustained Remission in Patients with Pemphigus Vulgaris
Genentech, a member of the Roche Group, announced positive top line results from the Roche-sponsored Phase III PEMPHIX study evaluating the efficacy and safety of Rituxan compared to mycophenolate mofetil, or MMF, in adults with moderate to severe pemphigus vulgaris, or PV.
The term "pemphigus" covers a family of immune problems, but the foliaceous version is the most common autoimmune skin disease.
WASHINGTON -- An investigational molecule that blocks the downstream proinflammatory effects of B cells controlled disease activity and induced clinical remission in patients with pemphigus by 12 weeks.
Pemphigus is a group of autoimmune, intraepithelial, chronic blistering skin diseases characterised by loss of normal intercellular adhesion.
Keywords: Pemphigus vulgaris, pemphigus foliaceus, dexamethasone-cyclophosphamide pulse therapy, dexamethasone pulse therapy, dexamethasone-methotrexate pulse therapy.