penicillamine


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Related to penicillamine: penicillin

pen·i·cil·la·mine

 (pĕn′ĭ-sĭl′ə-mēn′)
n.
A chelating agent, C5H11NO2S, that is a degradation product of penicillin and is used in the treatment of Wilson disease, refractory rheumatoid arthritis, and excess urinary excretion of cystine.

penicillamine

(ˌpɛnɪˈsɪləˌmiːn)
n
(Pharmacology) pharmacol a metabolite of penicillin, being a pyridoxine inhibitor and chelating agent, usually used as an anti-inflammatory in the treatment of arthritis

pen•i•cil•la•mine

(ˌpɛn əˈsɪl əˌmin, -mɪn)

n.
a chelating agent produced by the degradation of penicillin, used esp. to treat rheumatoid arthritis and lead poisoning.
[1943]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.penicillamine - a drug (trade name Cuprimine) used to treat heavy metal poisoning and Wilson's disease and severe arthritis
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
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References in periodicals archive ?
Idiosyncratic renal damage may be secondary to NSAIDs, penicillins, gold and penicillamine.
Several medications have been known to induce scleroderma-like clinical conditions including bleomycin, docetaxel, and penicillamine.
Chelating agents, such as penicillamine (Cuprimine[R]) and gold compounds, such as auranofin (Ridaura[R]) are used to decrease inflammation and to slow the destruction of joint tissue.
There are six agents available to treat heavy metal (arsenic, gold, iron, lead, and mercury) intoxication: de-ferasirox (iron), deferoxamine (iron), dimercaprol (arsenic, gold, lead, and mercury), edetate calcium disodium (lead), penicillamine (copper and mercury), and succimer (lead).
Drugs associated with pleural effusions Rare * Amiodarone * Phenytoin * Methotrexate Very rare * Carbamazepine * Cyclophosphamide * Penicillamine
PROCYSBI is contraindicated in patients with hypersensitivity to penicillamine.
A formal analysis of estimated continuation of 1,083 courses of six DMARDs over 60 months in 477 patients with RA indicated that approximately 80% of MTX courses were continued after 2 years, compared to 50% of courses of hydroxychloroquine, penicillamine, parenteral gold, and azathioprine and only 20% of courses of oral gold.
The pharmacological agent which are selected for evaluating in this study is Penicillamine, which their selection rationale will be discussed in detail separately in the following sections.
Degos R, Touraine R, Belaich S, Reva J: Pemphigus in a patient treated with penicillamine for Wilson's disease.
These include abatacept, adalimumab, anakinra, azathioprine, cyclophosphamide, cyclosporine, etanercept, gold, hydroxychloroquine, infliximab, leflunomide, methotrexate, minocycline, penicillamine, rituximab, and sulfasalazine.