penicillamine


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Related to penicillamine: penicillin

pen·i·cil·la·mine

 (pĕn′ĭ-sĭl′ə-mēn′)
n.
A chelating agent, C5H11NO2S, that is a degradation product of penicillin and is used in the treatment of Wilson disease, refractory rheumatoid arthritis, and excess urinary excretion of cystine.

penicillamine

(ˌpɛnɪˈsɪləˌmiːn)
n
(Pharmacology) pharmacol a metabolite of penicillin, being a pyridoxine inhibitor and chelating agent, usually used as an anti-inflammatory in the treatment of arthritis

pen•i•cil•la•mine

(ˌpɛn əˈsɪl əˌmin, -mɪn)

n.
a chelating agent produced by the degradation of penicillin, used esp. to treat rheumatoid arthritis and lead poisoning.
[1943]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.penicillamine - a drug (trade name Cuprimine) used to treat heavy metal poisoning and Wilson's disease and severe arthritis
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
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References in periodicals archive ?
Trientine hydrochloride and penicillamine cannot be considered interchangeable.
Penicillamine challenge test in the diagnosis of Wilson's disease.
The use of trientine in preventing the effects of interrupting penicillamine therapy in Wilson's disease.
Drug-induced EPS was commonly associated with the use of penicillamine as previously observed by several reports.
Another important chelator, which is used in patients with severe emesis where oral administration of D penicillamine is not possible is BAL.
Some of the associated conditions can be remembered with the mnemonic MADPPORES: Marfan syndrome, Acrogeria, Down syndrome, Penicillamine, Pseudoxanthoma elasticum, Osteogenesis imperfecta, Rothmund-Thomson syndrome, Ehlers-Danlos (some forms), and Scleroderma.
Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma.
3 This neuropathy is most common in high-risk patient population that includes slow acetylators, patients with HIV, diabetes, chronic renal failure, pregnant and lactating women, malnourished and elderly patients, alcoholics, patient on certain medications that antagonize B6 effect like hydralazine, cycloserine, penicillamine and antiretroviral drugs.
Idiosyncratic renal damage may be secondary to NSAIDs, penicillins, gold and penicillamine.
Several medications have been known to induce scleroderma-like clinical conditions including bleomycin, docetaxel, and penicillamine.
16) Some of the other medications that have been tested as a single agent in the treatment of PBC include chlorambucil, penicillamine, cyclosporine, corticosteroids, azathioprine, mycophenolate mofetil, thalidomide, methotrexate, malotilate, and colchicine.
Chelating agents, such as penicillamine (Cuprimine[R]) and gold compounds, such as auranofin (Ridaura[R]) are used to decrease inflammation and to slow the destruction of joint tissue.