pentapeptide


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pen·ta·pep·tide

 (pĕn′tə-pĕp′tīd)
n.
A polypeptide composed of five amino acids.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

pentapeptide

(ˌpɛntəˈpɛptaɪd)
n
(Biochemistry) biochem a polypeptide consisting of five amino acids
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Keywords: Pseudomonas aeruginosa, Qnr Gene, Pentapeptide Repeat Protein, Fluoroquinolone, Antibiotic Resistance
Pentapeptide, AAAAA, GGGGG, SSSSS, and YYYYY were synthesized by Hangzhou Kevin Biology, using alanine, glycine, serine and tyrosine as substrates, respectively.
Biochemical characterization of aspartyl phosphate phosphatase interaction with a phosphorylated response regulator and its inhibition by a pentapeptide. J Biol Chem.
(1999) The endogenous sulfated pentapeptide phytosulfokine-a stimulates tracheary element differentiation of isolated mesophyll cells of zinnia.
Lipases also share a consensus pentapeptide sequence of Gly-X-Ser-X-Gly motif, whereby X may be any amino acid residue [14].
There are two regulatory characteristics of ampR: in the absence of a [beta]-lactam inducer, it binds to the UDP-MurNAc pentapeptide to promote the formation of an AmpR-DNA complex that represses ampC transcription, while in the presence of a [beta]-lactam antibiotic, peptidoglycan fragments accumulate in the cytoplasm [10], and the 1,6-anhydro-MurNAc tripeptide (or pentapeptide) competitively displaces the UDP-MurNAc pentapeptide and converts AmpR into an activator, triggering the ampC expression or production of [beta]-lactamase [9].
maltophilia has identified a novel family of resistance genes (smqnr) encoding proteins containing pentapeptide repeats, which confer low-level resistance to quinolones (10).
The RUNX2 mutation resulted in the absence of the NMTS domain and C-terminal pentapeptide VWRPY.
It can effectively inhibit the secretion of gastric acid caused by histamine, pentapeptide gastrin, and the stimulation of food and reduce the activity of pepsin.
In addition, unlike the tested serine proteases, the enterokinase recognizes pentapeptide (DDDDY) rather than a single amino acid residue, meaning that masking of even one of the amino acids in the target site could cause resistance against enterokinase.
The D-Phe (f) and Lys (K) residues completed the cyclic and the pentapeptide structure, and Cys (C) is the spacer that contains the active thiol group that interacts with the gold nanoparticle surface.
Cilcane is a pentapeptide drug with an excellent safety profile and a novel mechanism of action compared to existing myeloma treatments, Research suggests the product will be synergistic in combination with a proteasome inhibitor, a class of drug normally given as a front line treatment for this disease and that this approach can also be extended to the treatment of other cancers, including breast cancer.