pentobarbital sodium


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pen·to·bar·bi·tal sodium

 (pĕn′tə-bär′bĭ-tôl′, -tăl′)
n.
A barbiturate, C11H17N2O3Na, that takes effect relatively rapidly, used as a sedative, a hypnotic, and an anticonvulsive drug, and for euthanasia. Also called pentobarbitone.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

pentobarbital sodium

,

pentobarbital

or

pentobarbitone

n
(Pharmacology) a barbiturate drug used in medicine as a sedative and hypnotic. Formula: C11H17N2O3Na. US equivalent: sodium pentabarbital
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pentobarbital sodium - a barbiturate (trade name Nembutal) used as a sedative and hypnotic and antispasmodic
barbiturate - organic compound having powerful soporific effect; overdose can be fatal
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
The animals were killed by pentobarbital sodium injection (100 mg/kg, iv) after the procedure.
Rats were given the intraperitoneal injection of pentobarbital sodium (150 mg/kg) for anaesthesia.
When the rats were 13 weeks old, we performed the intravenous glucose tolerance test (IVGTT), after which the rats were euthanized by exsanguination under anesthesia with pentobarbital sodium (60 mg/kg IP; Kyoritsu Seiyaku, Tokyo, Japan).
Mice were anesthetized with 0.007 g/mL pentobarbital sodium by intraperitoneal injection (50mg/kg body weight).
24 hours later, mice were deeply anaesthetized with 1% pentobarbital sodium on the basic of weight for subsequent experiments.
All surgical extractions and experimental procedures were performed under general anesthesia induced by an intravenous injection of 3% pentobarbital sodium solution (pentobarbital sodium salt, 0.4 ml/kg; Guoan Biotechnology Co., Ltd., Shaanxi, China) and an intramuscular injection of xylazine (0.05 ml/kg; Huamu Animal Health Products Co., Ltd., Jilin, China).
After six weeks of drug therapy, all mice were euthanized by intraperitoneal injection with 0.1% pentobarbital sodium. The hearts were extracted, and one-third of the heart was fixed in 10% formaldehyde to determine the morphology of any atherosclerotic plaque by hematoxylin and eosin (HE) staining.
Pentobarbital sodium and dimethylbenzanthracene (DMBA) were AP quality from Sinopharm, China.
3% pentobarbital sodium (1mL/kg body weight, Sigma, USA) was used for the anesthesia of the animals.
The following reagents and drugs were used: EtOH (AR), petroleum ether(AR) [CH.sub.2][CL.sub.2] (AR), n-butanol (AR), formalin (AR) and acetic acid (AR) [Sinopharm chemical reagent Co., Ltd., China], morphine hydrochloride, acetyl-salicylic acid, pentobarbital sodium (Sihuan Pharmaceutical Factory, Beijing, China), diazepam, naloxone, glibenclamide.
The animals were anesthetized by intraperitoneal injection of 30mg/kg pentobarbital sodium, sacrificed and the tongues were excised carefully.
Review of the literature yielded numerous articles addressing the medical management of RICH and patients treated with pentobarbital sodium coma.