DHAP is an important metabolite as a source of triglyceride synthesis and the
pentose phosphate pathway [20], and thus the change in DHAP content might influence multiple metabolic pathways.
Suzuki (1985).Red cell metabolism in experimental animal:
pentose phosphate pathway, antioxidant enzymes and glutathione.
[13] The absorbed xylitol, on the other hand, is phosphorylated and metabolized in the liver to xylulose 5-phosphate, an intermediate branch of the
pentose phosphate pathway, which connects the pathway of xylitol to glucose and cholesterol.
A total of 77 pathways, such as glycolysis/gluconeogenesis, TCA cycle, and
pentose phosphate pathway (Table S2), have more than five genes in the human genome.
Hay, "The
pentose phosphate pathway and cancer," Trends in Biochemical Sciences, vol.
G6PD, and the
pentose phosphate pathway (PPP) for which it serves as gate keeper, represents a principal generator of the NADPH needed for both biomass production and protection from Reactive Oxygen Species (ROS).
Furthermore, Nrf2 activation resulted in upregulation of gene expression of enzymes involved in [H.sub.2][O.sub.2] and free radical scavenging, such as catalase, thioredoxin-1, and the
pentose phosphate pathway intermediate enzyme 6-phosphogluconate dehydrogenase (PGD) (Figures 4(d), 4(e), and 4(f)).
Xylulose-5-P was further entered into the endogenous
pentose phosphate pathway (PPP) to produce ethanol.
During construction, a novel
pentose phosphate pathway (PPP) for the generation of ribulose-5-phosphate (R5P) was predicted and later verified.
G6PD catalyzes the first step of the
pentose phosphate pathway, one function of which is to protect cells against oxidative damage [2, 4].