pentose phosphate pathway


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pentose phosphate pathway

n
(Biochemistry) a sequence of metabolic reactions by which NADPH is synthesized, together with ribose phosphate, part of the synthesis of nucleic acids
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References in periodicals archive ?
DHAP is an important metabolite as a source of triglyceride synthesis and the pentose phosphate pathway [20], and thus the change in DHAP content might influence multiple metabolic pathways.
Suzuki (1985).Red cell metabolism in experimental animal: pentose phosphate pathway, antioxidant enzymes and glutathione.
[13] The absorbed xylitol, on the other hand, is phosphorylated and metabolized in the liver to xylulose 5-phosphate, an intermediate branch of the pentose phosphate pathway, which connects the pathway of xylitol to glucose and cholesterol.
A total of 77 pathways, such as glycolysis/gluconeogenesis, TCA cycle, and pentose phosphate pathway (Table S2), have more than five genes in the human genome.
Hay, "The pentose phosphate pathway and cancer," Trends in Biochemical Sciences, vol.
G6PD, and the pentose phosphate pathway (PPP) for which it serves as gate keeper, represents a principal generator of the NADPH needed for both biomass production and protection from Reactive Oxygen Species (ROS).
Furthermore, Nrf2 activation resulted in upregulation of gene expression of enzymes involved in [H.sub.2][O.sub.2] and free radical scavenging, such as catalase, thioredoxin-1, and the pentose phosphate pathway intermediate enzyme 6-phosphogluconate dehydrogenase (PGD) (Figures 4(d), 4(e), and 4(f)).
Xylulose-5-P was further entered into the endogenous pentose phosphate pathway (PPP) to produce ethanol.
During construction, a novel pentose phosphate pathway (PPP) for the generation of ribulose-5-phosphate (R5P) was predicted and later verified.
G6PD catalyzes the first step of the pentose phosphate pathway, one function of which is to protect cells against oxidative damage [2, 4].