pentose phosphate pathway

(redirected from pentose phosphate shunt)
Also found in: Medical, Encyclopedia.

pentose phosphate pathway

n
(Biochemistry) a sequence of metabolic reactions by which NADPH is synthesized, together with ribose phosphate, part of the synthesis of nucleic acids
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
metabolism can be made from glucose via the pentose phosphate shunt
This occurs because of decreased flux through pentose phosphate shunt thus depleting the cells of NADPH.
It has been demonstrated that the cytosolic NAD (P)- dependent dehydrogenases6 and NADP malic enzyme are inhibited by MTX, indicating that the drug could decrease the availability of NADPH in cells by inhibiting pentose cycle enzymes.7 Due to the interference with the pentose phosphate shunt, MTX may also depress nucleic acid metabolism.