pentose phosphate pathway

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pentose phosphate pathway

n
(Biochemistry) a sequence of metabolic reactions by which NADPH is synthesized, together with ribose phosphate, part of the synthesis of nucleic acids
References in periodicals archive ?
7 Due to the interference with the pentose phosphate shunt, MTX may also depress nucleic acid metabolism.
1) G6PD catalyzes the first oxidation reaction in the pentose phosphate shunt, in which glucose-6-phosphate is dehydrogenated to 6-phosphogluconolactone with the concurrent reduction of nicotinamide adenine dinucleotide phosphate (NADP).