pepsinogen

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Related to pepsinogen: trypsinogen

pep·sin·o·gen

(pĕp-sĭn′ə-jən)

The inactive precursor to pepsin, formed in cells of the mucous membrane of the stomach and converted to pepsin by autocatalysis in the presence of hydrochloric acid.

pepsinogen

(pɛpˈsɪnədʒən)

(Biochemistry) the inactive precursor of pepsin produced by the stomach

pep•sin•o•gen

(pɛpˈsɪn ə dʒən, -ˌdʒɛn)

n.

a crystalline proenzyme of the gastric glands, converted to pepsin during digestion.

[1875–80]

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Noun

pepsinogen - precursor of pepsin; stored in the stomach walls and converted to pepsin by hydrochloric acid in the stomach

enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions

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References in periodicals archive ?

2002) Serum levels of amidated gastrin-17 and pepsinogen I in atrophic gastritis.

Serological criteria for mild, moderate and severe atrophy in atrophic gastritis

Reformation of reduced disulfide bonds of pepsinogen and pepsin: role of the phosphate group.

Una peptidasa acida, insensible a inhibidores clasicos, en extractos proteicos de Trypanosoma cruzi, proveniente de una zona rural de Venezuela, endemica para la enfermedad de chagas

The tissues of first batch of 1 kg wet weight were incubated at 40[degrees]C for 24 h and the other batch was incubated at 40[degrees]C for 48 h for the conversion of pepsinogen into pepsin.

Variation in activity of pepsin extracted from buffalo stomach mucosa

58) When I was working at the Rockefeller University, structure-function studies of porcine pepsinogen A and pepsin A were in progress there in the laboratory of S.

Structure and function studies on enzymes with a catalytic carboxyl group(s): from ribonuclease [T.sub.1] to carboxyl peptidases

The effect of 5-year vitamin C supplementation on serum pepsinogen level and Helicobacter pylori infection.

A better form of vitamin C

pylori infection, the virulence factor cytotoxin-associated gene A (cagA), and gastric atrophy measured by the pepsinogen 1 to 2 ratio and fasting gastrin-17 levels alongside other known risk factors for gastric cancer.

Gastric adenocarcinoma in Zambia: a case-control study of HIV, lifestyle risk factors, and biomarkers of pathogenesis

Gastric cancer screening using the serum pepsinogen test method.

Tamizacion de cancer gastrico

The finding of a low pepsinogen I level in the serum is a sensitive and specific indicator of gastric atrophy.

Gastritis and gastropathy: more than meets the eye: this paper discusses the different types of gastritides and gastropathies, focusing on their wide range of aetiologies

Metzler and Mosenthin (2009) argued that the supplementation with organic acids for weaned piglets leads to a decrease in stomach pH, with optimal values between 3 and 4, easing the activation of pepsinogen to pepsin, and as a result the protein digestibility can be improved, as well as the gastric retention.

Growth performance and digestibility of juvenile Nile tilapia fed diets containing acid silage viscera of surubim catfish/Desempenho e digestibilidade de racoes contendo silagem acida de visceras de surubim para juvenis de tilapia-do-nilo

It is believed that the variation in quantity of serum- pepsinogen is in relation to the size of gastric secretory-cell mass.

Relationship between blood groups and ulcers: Revisiting the pioneer work

The acid secretions of the stomach are composed mainly of water, hydrochloric acid (HCl) and pepsinogen, with a pH of 1 to 2.

Treating nausea and vomiting

Although this source [previously cited] highlights that HCl itself has no effect in protein digestion directly, but can only convert pepsinogen to pepsin and denature food; our results prove [to] us that HCl has a more significant effect in the breakdown.