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Related to pepsinogen: trypsinogen


The inactive precursor to pepsin, formed in cells of the mucous membrane of the stomach and converted to pepsin by autocatalysis in the presence of hydrochloric acid.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) the inactive precursor of pepsin produced by the stomach
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(pɛpˈsɪn ə dʒən, -ˌdʒɛn)

a crystalline proenzyme of the gastric glands, converted to pepsin during digestion.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pepsinogen - precursor of pepsin; stored in the stomach walls and converted to pepsin by hydrochloric acid in the stomach
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
pylori antibody and serum pepsinogen (PG) has been implemented in Nishitokyo city from 2011 on the initiative of Nishitokyo Medical Association.[20] In comparison of the conventional mass screening, the ABC method not only increases the EGC detection rate but also reduces the screening cost.[21],[22],[23]
Serum TFF3 was shown to be a better potential screening tool for gastric cancer than pepsinogen in Japan [11].
Flavonoid-based biocompounds were also reported to promote formation of the gastric mucosa, inhibit pepsinogen production, decrease acid mucosal secretion, and reduce ulcerogenic lesions [53].
Yuan, "Association between pepsinogen C gene polymorphism and genetic predisposition to gastric cancer," World Journal of Gastroenterology, vol.
review the current evidence about the use of "ABC method," a combination of anti-Helicobacter pylori antibody and serum pepsinogen (PG), for gastric cancer screening.
Secretion of peptide hormones and pepsinogen into the circulation and muriatic acid into gastric lumen decreases at H.
In OME patients, pepsinogen and pepsin were detected in the middle ear fluid and the possibility of gastric fluid presence in the middle ear and its role in pathogenesis of OME was proposed.
Pepsin is a monomeric L-protein with a high percentage of acidic residues (43 out of 327) leading to a very low pH of 1.5-2.0, and is expressed as a prototype of zymogen and pepsinogen and is released by the chief cells in the stomach to degrade food proteins into peptides (Wang et al.
Most of the cells found in the tubular gastric glands are chief cells that secrete pepsinogen, an enzyme important for protein digestion.
Kuroda et al., "Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes," Endocrine Journal, vol.
Serum IL-6 levels and pepsinogen (PG) isozymes I and II were measured using a CLEIA (chemiluminescence enzyme immunoassay).
Inoue et al., "Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer," International Journal of Cancer, vol.