peptide bond


Also found in: Thesaurus, Medical, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to peptide bond: Dipeptide bond

peptide bond

n.
The chemical bond between carboxyl groups and amino groups of neighboring amino acids, forming an amide group and constituting the primary linkage of all protein structures.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

peptide bond

n
(Biochemistry) biochem a chemical amide linkage, –NH–CO–, formed by the condensation of the amino group of one amino acid with the carboxyl group of another
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.peptide bond - the primary linkage of all protein structures; the chemical bond between the carboxyl groups and amino groups that unites a peptide
bond, chemical bond - an electrical force linking atoms
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
These results indicated that the amino acid residue rather than the peptide bond on silk peptide might be mainly responsible for the photo-initiating function.
(1997) found that dipeptides are degraded more slowly than tri- and tetrapeptides due to preferential cleavage of certain peptide bonds. The microdialysis methodology employed in combination with the UHPLCMRM-MS quantification technique presented here opens up the possibility of monitoring and quantifying the turnover of individual LMW DON compounds in soil as fluxes of individual peptides and amino acids in future studies.
Protas et al., "Sequence-specific Ni(II)-dependent peptide bond hydrolysis for protein engineering: reaction conditions and molecular mechanism," Inorganic Chemistry, vol.
Microbial acid proteases exhibit specificity against aromatic or bulky amino acid residues on both sides of the peptide bond, which is similar to pepsin, but their action is less stringent than that of pepsin [4, 7].
Intermediate 6 would directly dehydrate between an amino group and a carboxy group to yield a peptide bond. Intermediate 8 would be attacked by an amino group to open its anhydride group and form two kinds of peptide bond that are linked using the [alpha]- and [beta]-carboxy groups; and then complete dehydration makes imide (10) bonds in polypeptides (9).
Crucially, the peptide bond hydrolysis improves the bioactivity of protein hydrolysates compared to their parent proteins, mainly due to the generation of bioactive peptides [31, 32].
(102) These studies indicated that the one-step and multiple-step activations may take place more or less simultaneously; the ratio of the two processes depends on the differences in the amino acid sequence of the propeptide followed by the N-terminal few residues of the pepsin moiety and the peptide bond specificity of the pepsin moiety.
Currently, the protein content of milk is analyzed through automated analyzers (SILVEIRA et al., 2004), which are based on the principle of mid-infrared (MIR) energy absorbance of protein specific chemical group, amides, at the approximately wavelength of 6.7 [micro]m (LYNCH et al., 2006) peptide bonds to estimate the concentration of CP (BARBANO & LYNCH, 2006).
Proteins are by definition chains of amino acids having a specific sequence and linked by peptide bonds. An amino acid residue is that part of an amino acid that is not incorporated into the peptide bond or protein chain.
Then, for MS-MS analysis, the peptides are broken into a series of constituent mixture of peptides by breaking them at each peptide bond in the chain.
Following an introduction to nomenclature and general mechanisms, chapters discuss mechanisms of CTI around the carbon-carbon double bonds via the triplet state; retinal binding proteins; non-retinal chromophoric proteins; fatty acids and phospholipids; in silico dynamic studies in organic and biological systems; chemical aspects of the restricted rotation of esters, amides, and related compounds; amide CTI in peptides and proteins; enzymes catalyzing peptide bond CTI; tailoring amides; peptidyl prolyl isomerases as new targets for novel therapeutics; and metal complexes.
One water molecule should be found on the floor below each peptide bond.