Since listing publicly on the Nasdaq Stock Market, Seelos has also acquired 2 Parkinson's Disease programs targeting the alpha-synuclein protein; SLS-007 which is a
peptidic inhibitor program and SLS-004 which is a gene therapy program targeting the SNCA gene.
The goal will be to establish in-vivo PK/PD and target engagement parameters of SLS-007, a family of anti-alpha-synuclein
peptidic inhibitors.
However, Moroz and colleagues also predicted dozens of novel putative
peptidic prohormones in P.
These results indicate that the hydrophilic portion of the biosurfactant molecule is likely to be
peptidic in nature.
Peptidic targeting of phosphatidylserine for the MRI detection of apoptosis in atherosclerotic plaques.
Antioxidant and antimicrobial
peptidic hydrolysates from muscle protein sources and by-products.
It provides great promise that these
peptidic extracts may significantly contribute to preserve the integrity of intestinal tissues against oxidative damage.
Deweid et al., "An apoptosis-inducing
peptidic heptad that efficiently clusters death receptor 5," Angewandte Chemie International Edition, vol.
Perret et al., "In vivo molecular imaging of atherosclerotic lesions in [apoE.sup.-/-] mice using VCAM-1-specific, 99mTc-labeled
peptidic sequences," Journal of Nuclear Medicine, vol.
Li-Chan, "Food-derived
peptidic antioxidants: a review of their production, assessment, and potential applications," Journal of Functional Foods, vol.
This piece of evidence led researchers to question if small
peptidic A[beta] "seeds" which are released from synaptic terminals in one brain region can trigger A[beta] accumulation in other regions.