Current research projects in the Cook Cardiopulmonary Engineering Group include thoracic artificial lungs, biofabricated tissue-based lungs, and
perfluorocarbon emulsions for pulmonary drug delivery.
As the refrigerants, we applied several types of non-conductive, thermally and chemically stable fluids, including silicone oil, soybean oil, and
perfluorocarbon structured refrigerant (Fluorinert, 3M Company).
Wickline, "Molecular Imaging With Targeted
Perfluorocarbon Nanoparticles: Quantification of the Concentration Dependence of Contrast Enhancement for Binding to Sparse Cellular Epitopes," Ultrasound in Medicine & Biology, vol.
Once a
perfluorocarbon liquid is added, the wicking process can lock the liquid on the surface and form a lubricating layer.
There are three major categories of substitute: gases (air, expansile gases), liquids (salt solution,
perfluorocarbon liquids, semifluorinated alkanes, silicone oil, etc.), and polymers (hydrogels, smart hydrogels, and thermosetting hydrogels) [15].
The majority of blood gas QC manufacturers use an aqueous buffered material or
perfluorocarbon emulsions solution.
Adhering the SLIPS coating to medical devices is a two-step process that begins with attaching a monolayer of
perfluorocarbon, a material similar to Teflon.
Its lead product, PHER-02, is an intravenous
perfluorocarbon emulsion that is highly efficient at dissolving and delivering oxygen to tissues.
[ClickPress, Thu May 07 2015] High Temperature Elastomers Market by Type (Fluorocarbon Elastomers, Fluorsilicone Elastomers,
Perfluorocarbon Elastomers, Silicone Elastomers, and Others), by Application (Transportation, Electrical & Electronics, Healthcare, Consumer Goods, Industrial Machinery, and Others) - Global Trends & Forecast to 2019
Operative technique included pars plana vitrectomy, proliferative vitreoretinopathy management, use of intraoperative
perfluorocarbon liquid, retinectomy, endolaser and intraocular temponade.
* Measurements of airflow between zones using
perfluorocarbon tracer (PFT) gas testing
Our results showed that liquid
perfluorocarbon administered endobronchially was able to improve lung preservation and reduced the deleterious effects of IR injury.
