The axon reaction: a review of the principal features of perikaryal
responses to axon injury.
Nitsch, "Loss of perikaryal
parvalbumin immunoreactivity from surviving GABAergic neurons in the CA1 field of epileptic gerbils," Hippocampus, vol.
Mushynski, "Aberrant stress-induced phosphorylation of perikaryal
neurofilaments," Journal of Biological Chemistry, vol.
If cell growth represents simply an increase in the perikaryal
area, the ratio of membrane protein to total protein would fall in parallel with the decline in the surface/volume ratio (volume increases with the cube of the perikaryal
radius, whereas surface area increases with the square of the radius).
This eventually results in two distinct cell clusters instead of a repetitive perikaryal
arrangement in the late sipunculan larva (Kristof et al, 2008; Wanninger et al, 2009).
Al-Abdulla AN, Leo JM (1998) Apoptosis of retrogradely degenerating neurons occurs in association with the accumulation of perikaryal
mitochondria and oxidative damage to the nucleus.
Typically, the localization of [Beta]III was diffuse within the individual tumor cells and was distributed equally in both the perikaryal
cytoplasm and in major fibrillated cell processes (Figure 2, a through f).
Typical AD neuropathological lesions include perikaryal
neurofibrillary tangles, which consist of paired helical filaments.
Although the immunoreactivity appeared more or less positive throughout the cells and cell processes, their perikaryal
somata and proximal processes were especially intensely immunostained where the immunoreactivity appeared in forms of numerous small granules.