(5) We defined a "perikaryon
" as a large cell with extensive, finely granular amphophilic cytoplasm, and a large nucleus with dispersed chromatin with or without a prominent nucleolus, and with or without accompanying sustentacular cells.
Furthermore, white matter degeneration is thought to be associated with functioning of nearby gray matter, as the nerve fibers convey signals from the cell's perikaryon
. Therefore, we maintain that the decrease in GFA values may be directly related to white matter denaturation and plastic changes associated with regaining cortical function.
In autistic children, dendritic branching of both CA4 and CA1 neurons was less than controls, and CA4 neurons were smaller in perikaryon
Experiments using the microtubule stabilizer Taxol show that, both in SC projecting neurons (present results) and in olfactory neurons , the retrograde activation of caspase-8 in the perikaryon
after axotomy depends on microtubule-based retrograde transport from the injured axon.
Besides, the study provided the analysis of pathological changes in neurons of the hippocampal CA1 region such as the presence of pyknotic hyperchromic neurons, shadow cells, neurons with focal hyperchromia of perikaryon
, neuronal disaggregation, and partial destruction of the cellular layer.
The normal cerebral cortex cells had pyramidal or spherical perikaryon
with large nuclei where the cells were arranged in a uniform pattern (Figures 5(a), 5(b), and 5(c)).
In addition, the immunostaining highlighted cells with short processes stemming from the round perikaryon
in a spoke wheel-like fashion (Figure 3, panel D).
Although in this study the mechanisms underlying the reductions in the number of cerebellar granule cells and decrease in the size of perikaryon
of purkinje cells were not investigated, however, it is known that glucocorticoids easily cross the blood-brain barrier and acts on CNS.
Dowson (1998) observed an increase in the mean total area of discrete regions of lipopigment in a Purkinje cell perikaryon
as age advances.
Aggregation of pigment perikaryon
and dispersion throughout the cytoplasm are the bases of the motile activities of an ordinary dendritic light-absorbing chromatophore.
The cells displayed small, spherical, and contracted bodies and a conical cytoplasm with branches resembling the neuronal perikaryon
, axon, and dendrite.
(1966) Preparation and characterization of nerve cell perikaryon
from rat cerebral cortex.