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The region between the cytoplasmic membrane and the outer cell membrane in gram-negative bacteria and some archaea.

per′i·plas′mic adj.


(Biology) biology the region between the outer wall and the inner cytoplasmic membrane of a biological (esp bacterial) cell
References in periodicals archive ?
The Company has successfully expressed antibody fragments, growth factors, antigens, enzymes and other proteins using multiple modes of expression including secretion (yeast), periplasmic secretion, soluble intracellular expression, and inclusion bodies.
Relative abundances of proteobacterial membrane-bound and periplasmic nitrate reductases in selected environments.
pastoris, etc), Eurogentec offers various development strategies based on protein refolding, periplasmic expression, and protein expression by secretion.
This "Trojan Horse" strategy allows S-649266 to enter the periplasmic space where it binds to penicillin-binding proteins (PBPs) and disrupts cell wall synthesis.
Furthermore, there is hydroxylamine oxidoreductase (HOA) enzyme, located in the periplasmic membrane which has a role in transforming NH2OH into N[O.
In fungi, the plasma membrane sits just inside of the periplasmic space under the cell wall.
CFTR is a member of the ATP-binding cassette (ABC) membrane transporter superfamily that includes proteins such as the multiple drug resistance protein (MDR) and bacterial periplasmic permeases (1, 3).
Characterization of periplasmic protein BP26 epitopes of Brucella melitensis reacting with murine monoclonal and sheep antibodies.
coli cells grown on normal medium displayed a cell wall composed of outer membrane and cytoplasmic membrane enclosing a periplasmic space.
pylori buffers protons and maintains a neutral periplasmic pH.
1 CFU per ml for four days, the cells maintained their intact membrane and continued to express genes, including stress sigma factor, periplasmic catalase, hemolysin and cold shock protein.
However, another mechanism of mucoid conversion is mediated by the activity of periplasmic proteases (such as MucD, AlgW, and Prc) that act directly on MucA, thereby decreasing its affinity for AlgT(U) and triggering alginate production.