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Related to peroxisomal: peroxisomal disease


A cell organelle containing a large number of enzymes, including catalase and oxidase, that break down long-chain fatty acids and other organic molecules. The hydrogen peroxide produced by these reactions is also broken down within the peroxisome.

per·ox′i·som′al (-sō′məl) adj.


(Biology) biology of or relating to a peroxisome; of the nature of a peroxisome
References in periodicals archive ?
The disease, for which there is no approved treatment, is caused by mutations in a peroxisomal transporter of very long chain fatty acids (VLCFA), known as ABCD1.
In addition, L-carnitine has other roles such as buffering the ratio of acyl-CoA to CoA, branched chain amino acid metabolism, removal of excess acyl groups, and peroxisomal fatty acid oxidation (Hoppel, 2003; Steiber et al.
Peroxisomal catalase requires hydrogen peroxide to oxidize alcohol.
PCE-specific experiments have provided evidence that peroxisomal markers are increased, but at dose levels (i.
In addition to CD27, Siva-1 can interact with the peroxisomal membrane protein (PMP22) (4), tyrosine kinase 2 (Tyk2) (5), pyrin (6), lysophosphatidic acid receptor 2 (LPA2) (7), the CVB3 capsid protein VP2 (8), and CD4 (9).
PH1 is an autosomal recessive metabolic condition caused by a congenital deficiency of alanine-glyoxylate aminotransferase (AGT), a hepatic peroxisomal enzyme.
Other intracellular sources of the generation of ROS include reactions involving cytochrome P450 enzymes (31), peroxisomal oxidases (32), and NAD(P)H oxidases (33).
The topics include the use of human embryonic stem cells in high-throughput toxicity assays, high-throughput screening assays to assess chemical phototoxicity, an automated soft agar colony formation assay for the high-throughput screening of malignant cell transformation, single-cell imaging cytometry-based high-throughput analysis of drug-induced cardiotoxicity, and evaluating the peroxisomal phenotype in high content toxicity profiling.
Peroxisomal oxidation of the steroid side chain in bile acid formation.
analysis ice Essential for confirmation of FAODs Laboratory investigations Tier 3 Plasma very long 1 ml heparin blood, on Essential for diagnosis chain fatty acids ice of X-ALD, pyridoxine - responsive epilepsy and peroxisomal disorders (e.