proliferator-activated receptor gamma (PPARI3), Nuclear regulatory factor 2 (NRF2), Oxidative stress, Developmental block, Maternal-to-zygotic transition.
These research and development efforts include potential combinations of elafibranor, a dual peroxisome
proliferator-activated alpha/delta agonist, with Terns' development candidates, including TERN-101, a farnesoid X receptor agonist, TERN-201, a semicarbazide-sensitive amine oxidase inhibitor, and their thyroid hormone receptor beta-selective agonist and apoptosis signal-regulating kinase 1 inhibitor programs.
proliferator-activated receptors (PPARs) belong to the superfamily of nuclear receptors which are are ligand-activated transcription factors.
It has been well-documented that fatty acids, especially PUFAs can regulate genes expression through binding to the intracellular peroxisome
Proliferator-Activated Receptors (PPARs) ".
proliferator-activated receptors (PPARs) are a family of transcription factors that are activated by several natural and synthetic ligands.
proliferator-activated receptors (PPARs), a subfamily of nuclear receptors, play a crucial role in regulating insulin sensitivity and may serve as potential therapeutic targets for AD.
is also an organelle that elicits antiviral innate immune responses through membrane-bounded MAVS [35, 36].
The agreement grants Reneo Pharmaceuticals exclusive worldwide rights to research, develop and commercialize vTv Therapeutics' selective peroxisome
proliferator-activated receptor delta (PPAR-delta) program.
Researchers from University of California - Davis Health System identified the host receptor peroxisome
proliferator receptor gamma (PPARg) as the regulator responsible for maintaining this cycle of protection.
The Sherpas, on the other hand, use only glucose because their cells contain a gene called PPAR1 (peroxisome
proliferator-activated receptor 1).
As an oral once-daily administered molecule and a first-in-class compound, it works using dual peroxisome
proliferator-activated alpha/delta pathways.