peroxisome


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per·ox·i·some

 (pə-rŏk′sĭ-sōm′)
n.
A cell organelle containing a large number of enzymes, including catalase and oxidase, that break down long-chain fatty acids and other organic molecules. The hydrogen peroxide produced by these reactions is also broken down within the peroxisome.


per·ox′i·som′al (-sō′məl) adj.

peroxisome

(pəˈrɒksɪˌsəʊm)
n
(Biochemistry) biology a type of organelle present in most eukaryotic cells that carry out oxidative reactions, such as oxidation of alcohol in the liver
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Keywords: Peroxisome proliferator-activated receptor gamma (PPARI3), Nuclear regulatory factor 2 (NRF2), Oxidative stress, Developmental block, Maternal-to-zygotic transition.
These research and development efforts include potential combinations of elafibranor, a dual peroxisome proliferator-activated alpha/delta agonist, with Terns' development candidates, including TERN-101, a farnesoid X receptor agonist, TERN-201, a semicarbazide-sensitive amine oxidase inhibitor, and their thyroid hormone receptor beta-selective agonist and apoptosis signal-regulating kinase 1 inhibitor programs.
Peroxisome proliferator-activated receptors (PPARs) belong to the superfamily of nuclear receptors which are are ligand-activated transcription factors.
It has been well-documented that fatty acids, especially PUFAs can regulate genes expression through binding to the intracellular peroxisome Proliferator-Activated Receptors (PPARs) ".
Peroxisome proliferator-activated receptors (PPARs) are a family of transcription factors that are activated by several natural and synthetic ligands.
Peroxisome proliferator-activated receptors (PPARs), a subfamily of nuclear receptors, play a crucial role in regulating insulin sensitivity and may serve as potential therapeutic targets for AD.
Peroxisome is also an organelle that elicits antiviral innate immune responses through membrane-bounded MAVS [35, 36].
The agreement grants Reneo Pharmaceuticals exclusive worldwide rights to research, develop and commercialize vTv Therapeutics' selective peroxisome proliferator-activated receptor delta (PPAR-delta) program.
Researchers from University of California - Davis Health System identified the host receptor peroxisome proliferator receptor gamma (PPARg) as the regulator responsible for maintaining this cycle of protection.
The Sherpas, on the other hand, use only glucose because their cells contain a gene called PPAR1 (peroxisome proliferator-activated receptor 1).
As an oral once-daily administered molecule and a first-in-class compound, it works using dual peroxisome proliferator-activated alpha/delta pathways.

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