perphenazine


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per·phen·a·zine

 (pər-fĕn′ə-zēn′)
n.
A crystalline compound, C21H26ClN3OS, used as a tranquilizer especially in the treatment of psychosis and to prevent or alleviate nausea and vomiting.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

perphenazine

(pəˈfɛnəˌziːn)
n
(Pharmacology) pharmacol a potent antipsychotic drug with formula C21H26ClN3OS, used to treat psychoses such as schizophrenia
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

per•phen•a•zine

(pərˈfɛn əˌzin, -zɪn)

n.
a crystalline, water-insoluble powder, C21H26ClN3OS, used as a tranquilizer and in treating intractable hiccups and nausea.
[1955–60; per- + phen (othi) azine]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.perphenazine - tranquilizer and antidepressant (trade name Triavil) sometimes used as an antiemetic for adults
antianxiety drug, anxiolytic, anxiolytic drug, minor tranquilizer, minor tranquilliser, minor tranquillizer - a tranquilizer used to relieve anxiety and reduce tension and irritability
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

perphenazine

n perfenazina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Chlorpromazine (Thorazine), clozapine (Clozaril), methotrimeprazine (Nozinan), olanzapine (Zyprexa), perphenazine (Trilafon), pimozide (Orap), quetiapine (Seroquel), thioridazine (Mellaril), and trifluoperazine (Stelazine).
Antipsychotic Drugs: Clozapine, Olanzapine, Perphenazine, Quetiapine, Thioridazine, Trifluoperazine, Loxapine, Methotrimeprazine, Molindone, Pimozide
Zhenghua, Study on the Inclusion Behavior of Sulfobutylether-[beta]-Cyclodextrin with Perphenazine by Flow Injection Chemiluminescence, Bull.
Common drugs metabolized by CYP3A46 Group of drugs Drug name Antidepressants (SSRIs; Citalopram, escitalopram, SNRIs; tricyclics; others) paroxetine, fluoxetine; venalafaxine, trazodone; amitriptyline, imipramine, clomipramine; buspirone nefazodone, mirtazapine Antipsychotics (first Haloperidol, perphenazine; generations; second aripiprazole, quetiapine, generations) risperidone, ziprasidone Benzodiazepines Alprazolam, diazepam, medazolam, temazepam, lorazepam, clonazepam Opiates Codeine, methadone, fentanyl, buprenorphine Hypnotics Zopiclone, zaleplon, zolpidem Antibiotics Erythromycin, clarithromycin, telithromycin Phosphodiesters Sildenafil, tadalafil inhibitors Table 2.
The affected drugs include: Azithromycin, Donepezil, Haloperidol, Imipramine HCl, Isosorbide Dinitrate, Naratriptan, Ondansetron, Perphenazine, and Risperidone.
McMillin, "Simultaneous UPLC-MS/MS assay for the detection of the traditional antipsychotics haloperidol, fluphenazine, perphenazine, and thiothixene in serum and plasma," Clinica Chimica Acta, vol.
chlorpromazine, and perphenazine. (175) There are also atypical
Perphenazine LAI and olanzapine LAI each brought a 42% reduction in rehospitalization risk; the oral version of perphenazine was associated with a 14% risk reduction.
One RCT (Zhu 2010) did not report details of APs use, but the remaining RCTs (Castro 2011; Shamir 2000; Shamir 2001) reported using a range of APs including levopromazine, haloperidol, clozapine, aripiprazole, olanzapine, quetiapine, risperidone, perphenazine, zuclopenthixol and chlorpromazine.
A limited number of patients switched from a typical to an atypical antipsychotic or were given exceptionally a typical antipsychotic during hospitalization: one patient received perphenazine (6 mg/day) (1/184; 0.54%), two patients were receiving pimozide (one at 2 mg/day and the second one at 4 mg/day) (2/184; 1.0%), two patients received promazine (50 mg/day and 240 mg/day, resp.) (2/184; 1.0%), and one patient was given zuclopenthixol (60 mg/day) (1/184; 0.54%).
Domanska, "PLGA biodegradable nanoparticles containing perphenazine or chlorpromazine hydrochloride: effect of formulation and release," International Journal of Molecular Sciences, vol.