TABLE 1 Antipsychotic agents and recommended dosages (5,8) Drug Dosage (mg/d) First-generation antipsychotics Chlorpromazine 300-1000 Haloperidol 5-20 Perphenazine
16-64 Second-generation antipsychotics Aripiprazole 10-30 Asenapine 5 Clozapine 150-600 Lurasidone 40-160 Olanzapine 10-30 Paliperidone 3-12 Quetiapine 300-800 Risperidone 2-8 Ziprasidone 120-200 TABLE 2 Long-acting injectable antipsychotics (21) Generic name Dose (mg) Frequency (weeks) Risperidone 25-50 Q 2 Paliperidone palmitate 34-234 Q 4 273-819 Q 12 Olanzapine pamoate 150-405 Q 2-4 Aripiprazole 300-400 Q 4 441-882 Q 4 Haloperidol decanoate 50-200 Q 4 Fluphenazine decanoate 12.
A double-blind randomized comparison of nortriptyline plus perphenazine
versus nortriptyline plus placebo in the treatment of psychotic depression in late life.
LAI and olanzapine LAI each brought a 42% reduction in rehospitalization risk; the oral version of perphenazine
was associated with a 14% risk reduction.
One RCT (Zhu 2010) did not report details of APs use, but the remaining RCTs (Castro 2011; Shamir 2000; Shamir 2001) reported using a range of APs including levopromazine, haloperidol, clozapine, aripiprazole, olanzapine, quetiapine, risperidone, perphenazine
, zuclopenthixol and chlorpromazine.
In patients with schizophrenia and metabolic syndrome, antipsychotic agents' that cause less weight gain such as quetiapine, aripiprazole, and atypical antipsychotics such as perphenazine
should be prescribed.
Metoclopramide, domperidone, perphenazine
, droperidol), haematological abnormalities (eg: prochlorperazine), sedation (eg: chlorpromazine, droperidol, cyclizine, etc.
These medications are chlorpromazine, haloperidol, perphenazine
, and fluphenazine.
The first three most commonly prescribed antipsychotic drugs were sulpiride, perphenazine
, and risperidone in 2002, olanzapine, risperidone, and quetiapine in 2006 and olanzapine, quetiapine, and risperidone in 2012.
Prescribed typical antipsychotics within the study period included chlorpromazine, clopenthixol, clothiapine, droperidol, flupentixol, fluphenazine, haloperidol, levomepromazine, loxapine, methotrimeprazine, perphenazine
, pipotiazine, sulpiride, thioridazine, thiothixene, and trifluoperazine.
I took my medications (lithium, perphenazine
, trihexyphenidyl, triazolam) and, thanks to them, I had no symptoms ("no disturbance of mood," my family physician wrote in his report to the psychiatrist), and I functioned pretty well (teaching full time).
Her current medication is based on perphenazine
10 ( ANI ): New studies in zebrafish have shown that a 50-year-old antipsychotic medication called perphenazine
can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia (ALL).