The primary diagnosis of the patient was made after she underwent a complete endocrinology workup in addition to the analysis of catecholamine excretion and localized tumour imaging to rule out the possibility of phaeochromocytoma
, a condition that results from a histological variant tumour of the same embryonic origin, typically mixtures of phaeochromocytoma
spindle cell sarcomas and adrenocortical carcinomas (3).
in pregnancy: anaesthetic management of combined caesarean section and tumor removal.
Lam, "Updates on the genetics and the clinical impacts on phaeochromocytoma
and paraganglioma in the new era," Critical Review in Oncology/Hematology, vol.
MRI was done only in cases of suspected phaeochromocytoma
. Hormonal evaluation included serum cortisol and 24-hour urine catecholamine in all cases.
(48.) Kimura N, Takayanagi R, Takizawa N, et al; Phaeochromocytoma
Study Group in Japan.
Diseases causing heart failure Hypertension Essential hypertension Unknown Secondary Primary aldosteronism (Conn syndrome), hypertension Cushing syndrome, phaeochromocytoma
, chronic kidney disease, renal artery stenosis, coarctation of the aorta, obstructive sleep apnoea Primary myocardial disease; cardiomyopathies and myocarditis HCM Familial Sporadic Obesity, infants of diabetic mothers, amyloid, athletes DCM Familial Non-familial Alcohol, pregnancy, tachymyopathy, thyrotoxicosis, myocarditis, nutritional (e.g.
Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultra performance liquid chromatographytandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma
. Ann Clin Biochem 2013;50:147-55.
Carotid body tumours, for example, may be associated with phaeochromocytoma
, however vagal paragangliomas are more commonly seen in familial syndromes, and are more likely to be multifocal.
Multiple endocrine neoplasia type 2 (MEN2) syndromes are autosomally dominant clinical associations characterised by a number of tumours, including medullary thyroid carcinoma (MTC), phaeochromocytoma
, thyroid C-cell hyperplasia (CCH), parathyroid tumours (MEN2A) and ganglioneuroma of the gastrointestinal tract (MEN2B).
She had had intermittent headache for a week, was scanned on a Wednesday, a phaeochromocytoma
was found, she came to work on the Friday, and passed away the next morning.
The Mayo criteria (all must be met) for diagnosis of this syndrome include the presence of transient left ventricle apical akinesis or dyskinesis, absence of obstructive coronary disease, new electrocardiographic abnormalities and absence of concurrent conditions such as head trauma, intracranial bleeding, phaeochromocytoma
, myocarditis and hypertrophic cardiomyopathy (15).
Dehydrobenzperidol is contraindicated in patients allergic to it, patients who are deeply sedated, and those with severe psychiatric depression or phaeochromocytoma
. Metoclopramide should not be administered to patients with epilepsy, bowel obstruction or perforation, or phaeochromocytoma