phenacetin


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Related to phenacetin: Paracetamol, aspirin

phenacetin

(fɪˈnæsɪtɪn)
n
(Pharmacology) a white crystalline solid formerly used in medicine to relieve pain and fever. Because of its kidney toxicity it has been superseded by paracetamol. Formula: CH3CONHC6H4OC2H5. Also called: acetophenetidin
[C19: from phenetidine + acetyl + -in]

phe•nac•e•tin

(fəˈnæs ɪ tɪn)

n.
a white, crystalline solid, C10H13NO2, formerly used to relieve pain and fever: withdrawn because of unfavorable side effects.
[1885–90; phen (etidine) + acet (yl) + -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.phenacetin - a white crystalline compound used as an analgesic and also as an antipyretic
analgesic, anodyne, pain pill, painkiller - a medicine used to relieve pain
References in classic literature ?
I'll take the phenacetin," she promised, "but I hate going to bed early.
Mr Criddle said Scurry had nearly seven grams of benzocaine, caffeine and phenacetin and six grams of paracetamol - commonly used for cutting drugs.
2-7) Other risk factors include pelvic irradiation, occupational exposure to chemicals from the aromatic amine family, and chronic phenacetin use.
Police also found heroin worth up to PS35,290, cocaine worth up to PS23,100 and stashes of benzocaine, caffeine, paracetamol and phenacetin, which are all used to "bulk out" drugs before they are sold.
Results: MA strongly inhibited CYPlA2-mediated phenacetin O-deethylation and CYP2B6-mediated bupropion hydroxylation with IC50 values of 3.
The majority of chemicals found in cocaine factories and labs consist of sulfuric acid, hydrochloric acid, sodium carbonate, caustic soda, ammonia, phenacetin, sodium metabisulfite, and isopropyl alcohol.
As a nurse prescriber, I am delighted to discover they were predominantly phenacetin, something else you may not choose to administer to an infant.
Phenacetin was a big success: Bayer developed a pharmaceutical division of their dye company and a new age began in the pharmaceutical industry with competitive branding and marketing of drugs.
They made an APC - aspirin, phenacetin, caffeine - powder as relief for colds, flu, arthritis and nerve pains.
The painkiller drug phenacetin was taken off the market long ago because of its severe kidney toxicity and increased risk of bladder cancer.
This concept of glomerulocystogenesis is based in part on studies of phenacetin toxicity, (17,159-162) but there is little objective evidence for a causative mechanism of glomerular cyst formation.
Common causes of acquired methaemoglobinaemia Acetanilid Naphthoquinone p-amino salicylic acid Naphthalene Aniline dyes Nitrites Benzene derivatives Nitroglycerin Clofazimine Nitric oxide Chlorates Nitrobenzene Chloroquine Paraquat Dapsone Phenacetin Local anaesthetic agents Phenazopyridine Metoclopramide Primaquine Methylene blue (paradoxically can transiently Sulfonamides worsen methaemoglobinaemia)