Injection cocktails of papaverine, phentolamine
and prostaglandin E1 vasoactive drugs can be used as monotherapy or combination therapy to produce erections suitable for intercourse (Coombs, Heck, Guhring, Narus, & Mulhall, 2012; Hawksworth & Burnett, 2015).
The patient was hemodynamically stabilized in the supine position with the administration of phentolamine
(a nonspecific a-adrenergic blocker) and metoprolol (a selective [sz]-antagonist).
and Nitroglycerin/Nitroprusside are the preferred drugs.
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Intravenous hypertensives such as sodium nitroprusside, phentolamine
or nicardipine are required for the treatment of acute hypertensive crisis, which can occur prior or during the operative procedure.
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Acute hypertensive crises are usually managed with Sodium nitroprusside (SNP), nitroglycerine, nicardipine and phentolamine
Two moments of hypertensive crisis occurred at minutes 30 and 50 of the surgery (mean arterial pressure of 122 and 160 mmHg, respectively) and were controlled with phentolamine
in bolus injections of 2 mg each.
In a large, retrospective study of nine hand surgeons' practices, looking at 3,110 cases of elective injection of low-dose epinephrine in hands and fingers, there were no cases of digital tissue loss or need for phentolamine
Patients who needed treatment with dopamine phentolamine
anisodamine or other vasoactive drugs were excluded from the study.
It contains Phentolamine
Mesylate, a short acting alpha-adrenergic blocker which causes vasodilatation of the endothelial smooth muscle.
Over 15 years later, the substitution of phentolamine
with chlorpromazine as an alpha-blocker in vasoactive cocktails for intracavernous injection therapy to treat ED was investigated.