phenylketonuric


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phen·yl·ke·to·nu·ri·a

 (fĕn′əl-kēt′n-o͝or′ē-ə, -yo͝or′-, fē′nəl-)
n. Abbr. PKU
A genetic disorder in which the body lacks the enzyme necessary to metabolize phenylalanine to tyrosine. Left untreated, the disorder can cause brain damage and progressive intellectual disability as a result of the accumulation of phenylalanine and its breakdown products.

[phenylketone, the class of organic compounds including phenylpyruvic acid, a breakdown product of phenylalanine that is abnormally abundant in the urine of those having the disorder (phenyl + ketone) + ur(o)- + -ia.]

phen′yl·ke′to·nu′ric adj. & n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

phenylketonuric

(ˌfiːnaɪlˌkiːtəʊˈnjʊərɪk) pathol
n
(Pathology) a person who is suffering from phenylketonuria or the condition in which the amount of phenylalanine in the blood cannot be regulated by the liver
adj
(Pathology) relating to the condition known as phenylketonuria in which the amount of phenylalanine in the blood cannot be regulated by the liver
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Behrakis, "Effect of diet on plasma total antioxidant status in phenylketonuric patients," European Journal of Clinical Nutrition, vol.
Measurement of neurotransmitter metabolites in the cerebrospinal fluid of phenylketonuric patients under dietary treatment.
Executive dysfunction in treated phenylketonuric patients.