phenytoin


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phen·y·to·in

 (fĕn′ĭ-tō′ĭn, fə-nĭt′ō-)
n.
An anticonvulsant drug, C15H12N2O2, used to treat epilepsy, often in the form of its sodium salt. Also called diphenylhydantoin.

[(di)pheny(lhydan)toin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

phenytoin

(ˌfɛnɪˈtəʊɪn)
n
(Pharmacology) an anticonvulsant drug used in the management of epilepsy and in the treatment of abnormal heart rhythms. Formula: C15H11N2O2Na. Also called: diphenylhydantoin sodium
[C20: from (di)pheny(lhydan)toin]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

phen•y•to•in

(ˌfɛn ɪˈtoʊ ɪn, fəˈnɪt oʊ-)

n.
a barbiturate-related substance, C15H12N2O2, used as an anticonvulsant in the treatment of epilepsy.
[1940–45; shortening of diphenylhydantoin= di-1 + phenyl + hydantoin a crystalline derivative of imidazole]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.phenytoin - an anticonvulsant drug (trade name Dilantin) used to treat epilepsy and that is not a sedative
hydantoin - any of a group of anticonvulsant drugs used in treating epilepsy
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

phenytoin

n fenitoína
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Immunohistochemical Analysis of the Role Connective Tissue Growth Factor in Drug-induced Gingival Overgrowth in Response to Phenytoin, Cyclosporine, and Nifedipine.
Before this study, the second line treatment was the anticonvulsant drug phenytoin, but until now this practice had never been scrutinised in a robust major randomised controlled trial.
For example, VPA is 93% protein-bound and phenytoin is 91% protein-bound.
The CMA argued that the companies held a dominant position in their respective markets manufacturing and supplying phenytoin sodium capsules.
After neurology consultation, 1000 mg phenytoin (loading dose of 15 mg/kg) in 250 mL of saline was intravenously infused over 45 min (infusion rate was in 22.2 mg/min and the concentration of phenytoin was 4 mg/mL).
Purple glove syndrome following intravenous phenytoin administration.
Results: Topiramate and phenytoin directly and indirectly reduced contractions in a time-dependent manner.
A single dose of 3.5 mg sodium phenytoin was injected in each egg of the experimental subgroup while controls were administered same volume of normal saline.
The most commonly prescribed initial AED in the study population was carbamazepine (n = 72), followed by phenytoin (n = 28), phenobarbitone (n = 13), levetiracetam (n = 13), and sodium valproate (n = 8).
Among numerous of ligands, especially Phenytoin and 6-(4-chlorophenyl) imidazo [2,1-b][1,3] thiazole-5-carbald-ehyde-(3,4-dichlorobenzyl) oxime (CITCO) have been reported as CAR agonists in primary hepatocytes (Peacock, 2005; Kublbeck et al., 2011).
A total of 50 patients inducted as a study group for the use of topical phenytoin powder, and the rest 50 were followed with a classical wound dressing with p-iodine and saline wash with magnesium sulfate dressing taken as a control group.
According to CMA, after Pfizer sold marketing rights for the drug to Flynn Pharma, the price of a 100-mg pack of phenytoin sodium skyrocketed to 67.50 pounds from 2.83 pounds.