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 (fŏs′fə-tās′, -tāz′)
Any of numerous enzymes that catalyze the removal of phosphate groups by hydrolysis of phosphate ester bonds. They act in the opposite manner to kinases and are important in metabolism and cell signaling.


(ˈfɒsfəˌteɪs; -ˌteɪz)
(Biochemistry) any of a group of enzymes that catalyse the hydrolysis of organic phosphates


(ˈfɒs fəˌteɪs, -ˌteɪz)

any of several classes of esterases of varying specificity that catalyze the hydrolysis of phosphoric esters.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.phosphatase - any of a group of enzymes that act as a catalyst in the hydrolysis of organic phosphates
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
References in periodicals archive ?
Dr Rita Tewari of the University of Nottingham has completed what she describes as a 'Herculean study', has said that the latest study identifies how protein phosphatases regulate parasite development and differentiation and the research provides a systematic functional analysis for all the 30 phosphatases in Plasmodium berghei, which is the parasite responsible for causing malaria in rodents.
2007) and excised roots as a source of native phosphatases (MacFall et al.
CEPTYR's world-leading expertise in protein tyrosine phosphatases has lead to the discovery and development of this important first-in-class compound.
As phosphatases like PP2A usually have the opposite biochemical function to kinase, the scientists predicted that PP2A would stop the tumour suppressor Polo and allow for unchecked cell growth.
The principle of the method involves the hydrolysis of 4-nitrophenylphosphate in the presence of magnesium ions by phosphatases
Protein phosphatases maintain the organization and structure interactions of hepatic keratin intermediate filaments.
Targets include: kinases, phosphatases, proteases, polymerases, COX/LOX, HDAC, HMG-CoA Reductase, nitric oxide synthase, and more.
7 /PRNewswire/ -- The next iteration of the "Protein Kinases & Phosphatases in Drug Discovery & Development," conference series, will take place in San Diego, CA on March 3-5, 2003, announces Strategic Research Institute.
Evidence that tartrate-resistant acid phosphatases from osteoclastomas and hairy cell leukemia spleen are members of a multigene family.
In particular, a multi-million dollar commitment has been made by companies towards the development of phosphatases shown to be associated with obesity and cancer.
PHILADELPHIA -- The leading industry and academic researchers of protein phosphatases will convene to discuss the latest research advances at the discovery, pre-clinical, and clinical stages at a new event entitled, "Protein Phosphatases as Therapeutic Targets," which will take place in Philadelphia, PA on September 26-27, 2002, announces Strategic Research Institute.
Improved electrophoretic resolution of bone and liver alkaline phosphatases resulting from partial digestion with neuraminidase.