b) Liver function tests: total bilirubin, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatise
, total proteins,
Antibodies against cyclinA, cyclinD1, Akt, p-Akt, GSK-3[beta], p- GSK-3[beta], phosphatise
, and PTEN were from Cell Signaling Technology (USA).
The maximum activity of acid and alkaline phosphatise
activity (ALP) was recorded under ZT and PB which was 10.57 and 9.3 % higher over CT, respectively.
1: the effect of icterogenin and rehmannic acid on bile flow and the excretion of bilirubin, phylloerythrin, coproporphyrin, alkaline phosphatise
and bromosulfalein," Proceedings of the Royay Society of London: Series B, Biological Sciences, vol.
Mean fasting alkaline phosphatise
level was 144.22+/-75.57, while mean random value was 174.15+/-96.70 (p=0.001).
Serum biochemistry revealed normal alanine aminotransaminase (ALT)-32.5 [+ or -] 4.92U/L (20-44U/L), bilirubin-0.725 [+ or -] 0.21U/L (0.2-1.2mg/dl), blood urea nitrogen (BUN)-13.5 [+ or -] 2.53mg/dl (7-18mg/ dl) and creatinine-0.475 [+ or -] 0.075mg/dl (0.3-0.6mg/ dl) and high alkaline phosphatise
(AKP)202.5 [+ or -] 41.1 U/L (131-321U/L).
It is likely that they act as inhibitors of these enzymes; the ability of phenolic compounds to inhibit the variety of enzymes like hydrolases, hyalouronidase, alkaline phosphatise
, arylsulphatase, cAMP phosphodiesterase, lipase, a- glucosidase, kinase have already been reported (Rani et al., 2009).
Elevated Prostatic acid phosphatise
serum concentrations; above 3ng/ml, can be observed in the patients with prostatic cancer and usually correlate with an advanced phase of the disease when the tumor penetrates the prostatic capsule.
Most cases are associated with a mutation in a multiple drug resistance (3) gene The diagnosis is often made by clinical history, and laboratory abnormalities generally include hyperbilirubinemia less than 6mg/dl The alkaline phosphatise
is always raised, and amino transferase levels may be 2 to 10times the upper limit of normal.
In addition, tissue samples from the pancreas and the proximal region of the jejunum were also collected to assess the tissue protein content (pancreas and jejunum), and specific activities of digestive enzymes (chymotrypsin amidase, maltase, sucrase, alkaline phosphatise
, and lipase).
The p value was significant in between serum calcium (p 0.004), haemoglobin (p 0,004), serum ferritin ( Less than 0.005) and alkaline phosphatise
( Less than 0.005).
Of these genes, ANP32E, a protein phosphatise
2A inhibitor with a role in chromatin remodelling and transcriptional regulation, is of particular interest as it has been shown to be independently associated with shortened survival .