phosphodiester bond

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phos·pho·di·es·ter bond

A covalent chemical bond that links two carbon atoms through a phosphate group, especially the bonds that link the pentose sugars of adjacent nucleotides in polynucleotide chains of RNA and DNA.

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Phosphodiesterases--a class of enzymes that break down the phosphodiester bond in second-messenger molecules, such as cyclic AMP and cyclic guanosine monophosphate (cGMP).
In a final step, DNA ligase III/XRCC1 heterodimer interacts with pol-[beta], displaces the polymerase, and catalyzes the formation of a new phosphodiester bond.
The human 2'-5'-Oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation.

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