Many animals can convert extra tryptophan (an amino acid) to niacin, but cats have large amounts of the enzyme picolinic acid
carboxylase that interferes with the conversion.
Briefly, through a series of enzymatic steps, tryptophan is normally converted into kynurenine, then to 3-hydroxykynurenine via kynurenine 3-monooxygenase (KMO; B2, NAD[P.sup.+]), then 3-hydroxyanthranilic acid is formed by kynureninase (KYNU; B6), and proceeds down the pathway to become either acetyl-coA, picolinic acid
or quinolinic acid, which is further converted into NA[D.sup.+] through another series of enzymatic steps.
Healthy people have normal ACMSD activity which leads to a balance in the production of picolinic acid
and quinolinic acid.
The results show the various organic acids present in the soil like (dl-Tartaric acid 5-Formylvanillic acid p-Phenylenediacetic acid 3 3-Dimethylacrylic acid r-Pentyloxybenzoic acid Glycolic acid Mesaconic acid Picolinic acid
along with other compounds of benzene.
. Picolinic acid
(PIC) is a six-member ring structure and isomer of nicotinic acid, containing five carbon atoms, a nitrogen, and a carboxyl group at position 2.
Saha, "Kinetics and mechanism of the picolinic acid
catalysed chromium(VI) oxidation of ethane-1, 2-diol in the presence and absence of surfactants," Transition Metal Chemistry, vol.
Among them were alkanes, 4 phenyl valeric acid, 5 isopentyl picolinic acid
, 3 hydroxylauric acid, (5 a, 3[beta]) 3-hydroxy-11-androstanone, 5[alpha]-2-en-11 androstenone, squalene, terpinol (a terpineol), menthol derivatives, palmitic, oleic and eicosanoic acids, and isoprenoid phytane.
is a naturally occurring end-product of L-tryptophan catabolism via the kynurenine pathway, and its production is catalyzed by picolinic carboxylase (MEHLER, 1956).
Unlike 5-HTP, L-tryptophan is a building block for protein synthesis and is also metabolized to important compounds such as niacin and picolinic acid
. Consequently, if a person is deficient in tryptophan, then supplementing with L-tryptophan would provide a broader spectrum of benefits than would treatment with 5-HTP.
2,4-D, 2,4-dichlorophenoxyacetic acid; Picloram, 4-amino-3,5,6-trichloro picolinic acid
To answer your other question, all zinc picolinate products contain zinc attached to picolinic acid
, which acts as a well-absorbed carrier.
Zinc is absorbed in the presence of picolinic acid
and Vitamin B6 is needed for this reaction to occur.