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A colorless or yellow poisonous compound, C11H16N2O2, obtained from the leaves of the jaborandi and used to induce sweating, promote salivation, and treat glaucoma.

[New Latin Pīlocarpus, jaborandi genus (Greek pīlos, wool, felt + Greek karpos, fruit; see -carp) + -ine.]


(ˌpaɪləʊˈkɑːpaɪn; -pɪn) or


(Elements & Compounds) an alkaloid extracted from the leaves of the jaborandi tree, formerly used to induce sweating. Formula: C11H16N2O2
[C19: from New Latin Pilocarpus genus name, from Greek pilos hair + karpos fruit]


(ˌpaɪ ləˈkɑr pin, -pɪn, ˌpɪl ə-)

an oil or crystalline alkaloid, C11H16N2O2, obtained from jaborandi, used chiefly to promote the flow of saliva or contract the pupil of the eye.
[1870–75; < New Latin Pilocarp(us) the genus of shrubs that includes jaborandi (< Greek pîlo(s) felt, wool or hair made into felt + -o- -o- + -karpos -carp) + -ine1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pilocarpine - cholinergic alkaloid used in eyedrops to treat glaucoma
alkaloid - natural bases containing nitrogen found in plants


n pilocarpina
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References in periodicals archive ?
Lithium in a 127 mg/kg dose [16,17,23] is often used to reduce the threshold for the induction of cholinergically induced seizures, such as with muscarinic agonist pilocarpine or irreversible inhibitor of acetylcholinesterase DFP in animal models of seizures.
3) The collection of sweat by quantitative pilocarpine iontophoresis, where cholinergic drugs are used as stimulators of sweat, is used as the follow-up of abnormal newborn screen and for the establishment of definitive diagnosis.
The bioengineered submandibular gland produced saliva in response to the administration of pilocarpine and gustatory stimulation by citrate, protected against oral bacterial infection and restored normal swallowing in a salivary gland defect mouse model.
The case was diagnosed as tonic pupil following trauma, and diluted pilocarpine 0.
The chemists also recovered tubes of Household Ointment from the 1930s, ophthalmic treatments and pain relievers such as pilocarpine nitrate, atropine and morphene, and anti-sickness medicine known as Avomine from 1955.
Dentists have the tools to detect and manage advanced periodontal disease and dental decay, and can prescribe salivary stimulants such as pilocarpine and cevimeline for patients with bad breath due to dry mouth.
Saliva substitutes can bring relief, as can oral pilocarpine or cevimeline, but relatively few patients seem to stick with them.
The anticonvulsant activity of American skullcap was determined in rat models of acute seizures induced by pilocarpine and pentylenetetrazol.
Pilocarpine is a nonspecific parasympathomimetic agent (GRAHN & STOREY, 2004).