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A colorless or yellow poisonous compound, C11H16N2O2, obtained from the leaves of the jaborandi and used to induce sweating, promote salivation, and treat glaucoma.

[New Latin Pīlocarpus, jaborandi genus (Greek pīlos, wool, felt + Greek karpos, fruit; see -carp) + -ine.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌpaɪləʊˈkɑːpaɪn; -pɪn) or


(Elements & Compounds) an alkaloid extracted from the leaves of the jaborandi tree, formerly used to induce sweating. Formula: C11H16N2O2
[C19: from New Latin Pilocarpus genus name, from Greek pilos hair + karpos fruit]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌpaɪ ləˈkɑr pin, -pɪn, ˌpɪl ə-)

an oil or crystalline alkaloid, C11H16N2O2, obtained from jaborandi, used chiefly to promote the flow of saliva or contract the pupil of the eye.
[1870–75; < New Latin Pilocarp(us) the genus of shrubs that includes jaborandi (< Greek pîlo(s) felt, wool or hair made into felt + -o- -o- + -karpos -carp) + -ine1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pilocarpine - cholinergic alkaloid used in eyedrops to treat glaucoma
alkaloid - natural bases containing nitrogen found in plants
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n pilocarpina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
Loss of pilocarpine effect on outflow facility following surgical disinsertion and retro-displacement of the scleral spur in the cynomolgus monkey.
The researchers are preparing to begin a clinical study of two drugs: pilocarpine, which effectively stimulates salivary glands to produce saliva but doesn't treat the underlying cause of the condition, and hydroxychloroquine, which reduces gland inflammation but does little to stimulate salivary function.
Features of the new Macroduct Advanced include a touch screen user interface with built-in step-by-step graphical instructions that further standardize pilocarpine iontophoresis and sweat collection for optimum results.
FDP was found to be more effective than KD and 2DG against seizures induced by pilocarpine, kainic acid, and PTZ.
Half of the animals were treated with pilocarpine hydrochloride (340 mg/kg, i.p.) at the age of 30 days in order to induce status epilepticus (PILO, Figures 1(a) and 2(a)).
Lithium chloride (125mg/kg body weight, i.p.; Amresco LLC, Solon, China) was used to enhance the sensitivity of pilocarpine, scopolamine (1 mg/kg body weight, i.p.; Tomax, Shenzhen, China) was injected 20 h later to limit cholinergic effects and the risk of unexpected death, and pilocarpine (200 mg/kg body weight, i.p.; Cayman, Ann Arbor, USA) was administered 30 min later.
Tear production was stimulated by intraperitoneal injection of 3 mg/kg pilocarpine (Santen, Osaka, Japan) at 1 minute after the anesthesia.
Importantly, epilepsy induced by pilocarpine in rodent models can provide information regarding oxidative stress-related epileptic activity [3, 4,16-18].
Statins have been shown to be neuroprotective in a group of animal disease models and clinical studies.11,17 Statins are shown to prevent hippocampal neuron death in kainic acid (KA), pilocarpine, pentylentetrasole and quinolinic acid (QA)-induced epileptic seizures.11,13
In keeping with the overall NBS notification and reporting practices, the designated follow-up person from the CF NBS program should identify the primary care provider (PCP), notify that person of the positive screen result, and recommend that the infant be referred for quantitative pilocarpine iontophoresis sweat testing, which is the diagnostic test for cystic fibrosis.
If nimodipine in preventing tonic convulsions caused by PTZ [5], Aminophyline [1] and pilocarpine [10] have a protective effect, but unlike the above models in all tests anticonvulsant effect has been observed.