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Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway.
Piperine induces hepatic low-density lipoprotein receptor expression through proteolytic activation of sterol regulatory element-binding proteins.
HOME CURE: Ground pepper USE IT FOR: Cuts STUDIES show a component of black pepper, called piperine, has strong antibacterial properties, which would suggest it is helpful for healing.
Caloric restriction favorably impacts metabolic and immune/inflammatory profiles in obese mice but curcumin/ piperine consumption adds no further benefit.
HOME CURE: Ground pepper USE IT FOR: Cuts STUDIES show a component of black pepper, called piperine, has strong anti-bacterial properties, which would suggest it is helpful for healing.
Black pepper possesses its own antioxidant phytochemical piperine, which increases bioavailability of other nutrients.
How it works: Piperine, the essential oil released when you grind up peppercorns, has anti-inflammatory and anti-bacterial properties - so gargle an infusion of freshly ground black pepper and water to soothe your pipes.
Under inhibitors of glucuronidation, there is an interesting aside about curcumin and piperine. Recall how for a period this was the hot combination that was claimed to enhance absorption 20-fold.
Another study indicated that low doses of FA combined with a subthreshold dose of piperine, a bioavailability enhancer, have synergistic antidepressant-like effect on depression-like behaviors in mice (42).