plasma cell


Also found in: Thesaurus, Medical, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.

plasma cell

n.
Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, and lymph nodes. Also called plasmacyte.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

plas′ma cell`


n.
an antibody-secreting cell, derived from B cells, that plays a major role in antibody-mediated immunity. Also called plas•ma•cyte (ˈplæz məˌsaɪt)
[1885–90]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

plasma cell

A cell that produces antibodies as part of an immune response. B cells develop into plasma cells. See Note at antibody.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigenplasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood
lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection
plasmablast - the precursor of a plasma cell
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Multiple myeloma is cancer that begins in plasma cells (white blood cells that produce antibodies) and may also be referred to as plasma cell myeloma.
Scattered lymphocytic and plasma cell infiltrates with abundant dense hyalinized collagenous stroma and focal small calcifications are seen.
angular, contact, exfoliative, actinic, glandular, granulomatous, plasma cell cheilitis, simplex, etc.
Background and Objectives: Monoclonal gammopathy of undetermined significance (MGUS) is the most prevalent among the group of disorders called Plasma cell dyscrasias.
The study was conducted using Plasma Cell Enrichment Technique, which is a more accurate mechanism for separating plasma cells from other cells during testing.
The diagnosis involves establishing high circulating levels of IgG4 > 135 mg/dL, increased serum IgG4 to IgG ratio of >8%, immunohistochemistry showing dense lymphoplasmacellular inflammatory infiltrate consisting of IgG4-positive plasma cells with storiform fibrosis and obliterative phlebitis, and increased IgG4 positive plasma cell > 10 cells per high-power field when at least three fields are evaluated and the IgG4/IgG ratio of RT is increased by varying degrees [7, 10].
Solitary bone plasmacytoma (SBP) is a localized plasma cell tumor accounting for 2-5% of plasma cell malignancies.
As there was no evidence to suggest a lymphoma or a plasma cell neoplasm, a diagnosis of IgG-related disease was considered.
Plasma cell myeloma (PCM) accounts for approximately 1.6% of all cancer cases and about 10% of all hematologic malignancies in the United States [1] and is characterized by the proliferation of malignant plasma cells and subsequent increase of a monoclonal paraprotein in serum.
The cells were collected at day 7 after CpG2216 stimulation and stained with fluorochrome-conjugated antibodies (anti-CD19-APC, anti-CD20-APC-Cy[gamma], and anti-CD38-PE C[gamma]7) for plasma cell analysis with flow cytometry.
Her medical history was significant for extranodal marginal zone lymphoma, plasma cell dyscrasia and amyloidosis diagnosed one year earlier following biopsy of a right cheek mass.
Histopathological findings showed an elevated number of mature plasma cells with an IgG4+/IgG+ plasma cell ratio >50% and the presence of numerous IgG4-positive plasma cells in the germinal zone without pathological lymphoid population.