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Related to plasmid: Plasmid DNA


A circular, double-stranded unit of DNA that replicates within a cell independently of the chromosomal DNA. Plasmids are most often found in bacteria and are used in recombinant DNA research to transfer genes between cells.


(Genetics) a small circle of bacterial DNA that is independent of the main bacterial chromosome. Plasmids often contain genes for drug resistances and can be transmitted between bacteria of the same and different species: used in genetic engineering
[C20: from plasm + -id1]


(ˈplæz mɪd)

a strand or loop of DNA that exists independently of the chromosome in bacteria and yeast and that is capable of genetic replication: used in recombinant DNA procedures as a vehicle of gene transfer.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasmid - a small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication
cellular inclusion, inclusion body, inclusion - any small intracellular body found within another (characteristic of certain diseases); "an inclusion in the cytoplasm of the cell"
References in periodicals archive ?
LineaRx offers a cleaner, potentially higher-performing alternative to plasmid DNAs with linear DNAs produced by PCR (Polymerase Chain Reaction) that are used to reprogram CAR T cells.
VGXI, Inc., GeneOne's wholly-owned manufacturing subsidiary located in Texas, is the largest pure-play cGMP DNA plasmid manufacturing facility in the world.
LineaRx believes this momentum reflects increasing interest across the biotech industry to pursue a cleaner, higher-performing alternative to plasmid DNAs that are produced by fermentation in bacteria.
Macherey-Nagel GmbH & Co KG said on Monday that it plans to develop an automated solution for the preparation of transfection grade plasmid DNA under a co-marketing agreement with Andrew Alliance.
Soil samples were found positive for plasmid DNA of Bacillus anthracis (CapB) in 3 villages (n= 3/1985, 0.15%), whereas plasmid DNA of Bacillus anthracis (PA) was detected in soil samples of 4 villages, (n=4/1985, 0.20%).
The synthetic plasmid was successfully co-transformed along with the helper plasmid pAL154 in Agrobacterium tumefaciens (strain AGL1).
"We store the bacteria, carrying the plasmid frozen in glycerol in 2D barcoded tubes in a -80[degrees]C freezer," explains Kory DelPrete, Laboratory Operations Manager.
Aldevron has launched an off-the-shelf version of pXX6-80, a common adeno-associated virus (AAV) helper plasmid. The plasmid is designed to reduce the cost of AAV manufacturing and subsequent gene therapy applications, while helping Aldevron's clients meet regulatory requirements.
Plasmid carry genes that could be spread by conjugation and transduction while the genome based resistant genes are also spread by replication.
amylovora ACW56400 plasmid pEI70 have been reported to increase growth rates in minimal medium with sucrose, thus improving competence and increasing pathogen aggressiveness [19].
In general, genetical alteration is carried out by the introduction of a recombinant DNA into the cell in the form of a plasmid [1].