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Related to plasmin: plasminogen, fibrinogen


A proteolytic enzyme that is formed from plasminogen in blood plasma and dissolves the fibrin in blood clots. Also called fibrinolysin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) a proteolytic enzyme that causes fibrinolysis in blood clots
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈplæz mɪn)

an enzyme in the blood that dissolves blood clots by breaking down fibrin. Also called fibrinolysin.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasmin - an enzyme that dissolves the fibrin of blood clots
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
plasminogen - an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
It can catalyze the cracking of plasminogen to plasmin which dissolves thrombi by degrading fibrin clots as well as the fibrinogen, coagulation factors V and VIII in blood circulation.
There is also a role of autologous plasmin enzyme in patients with BRVO.
Dissolution of thrombi is called fibrinolysis, which occurs by the action of an enzyme called plasmin. The plasminogen, the inactive form of plasmin, is activated by compounds called plasminogen activators.
OKLAHOMA CITY New research from the Oklahoma Medical Research Foundation has pinpointed the cause of liver bleeding during acetaminophen overdose.<br />OMRF scientists have also discovered a new potential treatment for the condition, which often strikes users of Percocet and Vicodin, pain medications that also contain acetaminophen, sold over the counter as Tylenol.<br />OMRF scientists Courtney Griffin and Siqi Gao discovered that a marked increase in the activity of an enzyme called plasmin caused liver bleeding in the event of acetaminophen overdose.<br />"It was well-known that acetaminophen, like most drugs, is metabolized in the liver," said Gao, who is also a Ph.D.
Both "tPA" and "TPA" are also used to denote the tissue plasminogen activator protein, the major enzyme responsible for catalyzing the conversion of plasminogen to plasmin (the targeted action of these recombinant medications).
To reduce the TBL, we should think of the cause of the HBL and how to reduce it.[1],[2] Recent studies suggested that prolonged fibrinolytic activity from delayed activation of plasmin beyond the initial surgical trauma might be a potential cause for HBL.[3],[4],[5]
Tranexamic acid " blocks keratinocytes from causing plasminogen to go into plasmin," and plasmin stimulates fibroblast growth factor production, which is "one of the most potent stimulants of melanin," he explained.
This system comprises a few proteins that by acting in sequence lead to the conversion of zymogenic plasminogen into its active enzymatic form, plasmin. Plasmin is a serine-protease capable of breaking down components of the extracellular matrix such as fibrin, fibronectin, laminins and vitronectin (Liotta et al., 1981).
Argatroban is highly selective for thrombin and has little or no effect on related serine proteases (trypsin, factor Xa, plasmin, and kallikrein).
The mechanism of action of TA in treatment of melasma is not completely understood but it seems to suppress UV-induced plasmin activity in keratinocytes.