Hesperidin can cut down atherosclerosis pleiotropically
, including improvement of insulin resistance, amelioration of lipid profiles, inhibition of macrophage foam cell formation, anti-oxidative effect and anti-inflammatory action(Sun et al., 2017).
Aida et al., "The PINHEAD/ ZWILLE gene acts pleiotropically
in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene," Development, vol.
At the same time, in such collection, negative correlation between culm diameter and tiller number per plant, which are pleiotropically
controlled by SL as discussed above, was also observed (Fig.
Baddour et al., "Tumor microenvironment derived exosomes pleiotropically
modulate cancer cell metabolism," eLife, vol.
Benaich, "A pleiotropically
acting microRNA, miR-31, inhibits breast cancer metastasis," Cell, vol.
A number of other pharmaceuticals pleiotropically
It has been reported that the GLP-1 analog, which is an incretin-related medication, shows antihyperglycemic action by enhancing insulin secretion from pancreatic [beta]-cells, but the unique effects of this treatment are pleiotropically
expected as extrapancreatic action including appetite loss, body weight loss, and delayed gastric emptying .
The discovery may be a reminder that traits are not always what they seem: In this case, the fundamental trait concerns senescent function; seed color is merely expressed pleiotropically
corolla morphology, and pollen rewards, may also be pleiotropically
Our analyses identified several pleiotropically
acting and epistatically interacting QTL, in addition to linked QTL, for seed traits targeted by selection in the transition from large-seeded, low-oil to small-seeded, high-oil cultivars (Fig.
Two QTLs on linkage groups C and E each displayed observable pleiotropic effects on basal area and volume index in Boardman, but only a QTL on linkage group J pleiotropically
affected these two traits in Clatskanie.
Head size and IQ show a WF correlation (358), as do myopia and IQ (299), suggesting that these two physical traits are pleiotropically
related to IQ.