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Related to pleiotropically: Negative pleiotropy


 (plī-ŏt′rə-pē) also plei·ot·ro·pism (-pĭz′əm)
n. Biology
The production of diverse effects, especially the production by a single gene of several distinct and seemingly unrelated phenotypic effects.

[Greek pleiōn, more; see pelə- in Indo-European roots + -tropism.]

plei′o·tro′pic (plī′ə-trō′pĭk, -trŏp′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(plaɪˈɒtrəˌpɪzəm) or


(Genetics) genetics the condition of a gene affecting more than one characteristic of the phenotype
pleiotropic adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Hesperidin can cut down atherosclerosis pleiotropically, including improvement of insulin resistance, amelioration of lipid profiles, inhibition of macrophage foam cell formation, anti-oxidative effect and anti-inflammatory action(Sun et al., 2017).
Aida et al., "The PINHEAD/ ZWILLE gene acts pleiotropically in Arabidopsis development and has overlapping functions with the ARGONAUTE1 gene," Development, vol.
At the same time, in such collection, negative correlation between culm diameter and tiller number per plant, which are pleiotropically controlled by SL as discussed above, was also observed (Fig.
Baddour et al., "Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism," eLife, vol.
Benaich, "A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis," Cell, vol.
It has been reported that the GLP-1 analog, which is an incretin-related medication, shows antihyperglycemic action by enhancing insulin secretion from pancreatic [beta]-cells, but the unique effects of this treatment are pleiotropically expected as extrapancreatic action including appetite loss, body weight loss, and delayed gastric emptying [4].
The discovery may be a reminder that traits are not always what they seem: In this case, the fundamental trait concerns senescent function; seed color is merely expressed pleiotropically.
corolla morphology, and pollen rewards, may also be pleiotropically
Our analyses identified several pleiotropically acting and epistatically interacting QTL, in addition to linked QTL, for seed traits targeted by selection in the transition from large-seeded, low-oil to small-seeded, high-oil cultivars (Fig.
Two QTLs on linkage groups C and E each displayed observable pleiotropic effects on basal area and volume index in Boardman, but only a QTL on linkage group J pleiotropically affected these two traits in Clatskanie.
Head size and IQ show a WF correlation (358), as do myopia and IQ (299), suggesting that these two physical traits are pleiotropically related to IQ.